InvisiScar Resurfacing Treatment Larger Size

DESCRIPTION

What It Does: Ascorbic acid neutralizes free radicals, stimulates collagen production, inhibits melanin synthesis for a brighter complexion, and supports skin repair.

Why It's Used: It is used because it offers comprehensive antioxidant and brightening benefits supported by extensive clinical evidence. it is the most bioavailable form of vitamin c for topical application.

How It Works: As an antioxidant, it donates electrons to neutralize reactive oxygen species. it is an essential cofactor for the hydroxylation of proline and lysine in collagen synthesis. it inhibits tyrosinase, the enzyme responsible for melanin production, reducing hyperpigmentation.

Typically Found In: Vitamin c serums,brightening moisturizers,antioxidant formulations,spf products,eye creams

TECHNICAL DETAILS

Primary Category: Active ingredient – vitamin c

Secondary Functions: Collagen booster,tyrosinase inhibitor,ph adjuster

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 5%–20% (effective range: 10–20%; ph must be below 3.5 for activity)

SOURCING & ETHICS

Vegan Status: Yes – synthetically produced or corn/plant-derived

Halal Status: Yes

Source Notes: Commercially produced by reichstein synthesis or guangxi fermentation process from glucose. some plant-derived versions exist.

SKIN COMPATIBILITY

Irritancy Rating: 2/5 – low to moderate; low ph formulations can cause initial tingling or stinging, especially at concentrations above 15%

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Acidic ph can irritate sensitive or compromised skin barriers. highly unstable – oxidizes rapidly when exposed to air, light, and heat (turns orange/brown). use in the morning under spf.

Safe for Sensitive Skin: Use with caution – start at lower concentrations (5–10%). stabilized derivative forms (vitamin c derivatives) may be better tolerated.

SAFETY & COMPATIBILITY

Safety Profile: Very safe; well-studied. key concern is formulation stability, not safety. ewg hazard score: 1.

Works Well With: Vitamin e (tocopherol) – synergistic antioxidant effect,ferulic acid – stabilizing and boosting,spf,hyaluronic acid,niacinamide (use at different times if concentrations are high)

Avoid Combining With: Retinol (use at separate times – ph incompatibility),benzoyl peroxide (oxidizes vitamin c),ahas/bhas (cumulative irritation risk)

SCIENTIFIC NOTE

L-ascorbic acid is the only form of vitamin c that is proven bioactive in skin at the molecular level. its instability (rapid oxidation) has driven development of numerous stable derivatives including ascorbyl glucoside, magnesium ascorbyl phosphate, and ascorbyl tetraisopalmitate.

Last Verified: Cosing database,cir safety assessment,pinnell et al. studies,journal of the american academy of dermatology

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Stimulates normal wound healing collagen synthesis while preventing excessive fibrosis and hypertrophic scar formation.

Why It's Used: Unique anti-fibrotic wound healing ingredient – stimulates collagen i and iii while reducing excessive tgf-β-driven fibrosis, making it ideal for preventing hypertrophic scars.

How It Works: Stimulates col1a1/col3a1 transcription in normal fibroblasts while inhibiting tgf-β-induced myofibroblast differentiation that drives hypertrophic scar formation. also inhibits nf-kb for anti-inflammatory activity.

Typically Found In: Scar prevention products,post-procedure recovery,wound healing

TECHNICAL DETAILS

Primary Category: Active ingredient – soothing / anti-inflammatory

Secondary Functions: Anti-fibrotic,scar prevention,collagen regulation

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.01%–1%

SOURCING & ETHICS

Vegan Status: Yes – from centella asiatica

Halal Status: Yes

Source Notes: Plant-derived extract or synthetic.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; ideal for reactive and sensitive skin.

Safe for Sensitive Skin: Yes – particularly recommended for sensitive skin

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Ceramides,panthenol,allantoin,hyaluronic acid,centella asiatica

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

The paradox of asiatic acid is its ability to both stimulate collagen synthesis (anti-aging) and prevent fibrosis (anti-scarring) from the same compound. this selective effect occurs because asiatic acid stimulates normal fibroblast collagen synthesis while specifically inhibiting tgf-β1-driven myofibroblast transformation – the cell type responsible for excessive scar tissue.

Last Verified: Cosing database,maquart et al. asiatic acid study

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Accelerates wound healing and reduces scar formation through fibroblast activation and collagen synthesis stimulation.

Why It's Used: Clinically proven scar reduction and wound healing active – the compound behind centella's legendary wound healing reputation.

How It Works: Promotes fibroblast proliferation and collagen synthesis via tgf-β independent mechanism (distinct from madecassoside). also inhibits hyaluronidase protecting extracellular matrix. antimicrobial activity supports wound healing environment.

Typically Found In: Post-surgical products,scar treatments,wound healing formulations

TECHNICAL DETAILS

Primary Category: Active ingredient – soothing / anti-inflammatory

Secondary Functions: Scar reduction,wound healing,collagen stimulation

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.01%–2%

SOURCING & ETHICS

Vegan Status: Yes – centella asiatica derived

Halal Status: Yes

Source Notes: Extracted from centella asiatica aerial parts alongside madecassoside, asiatic acid, and madecassic acid.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; ideal for reactive and sensitive skin.

Safe for Sensitive Skin: Yes – particularly recommended for sensitive skin

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Ceramides,panthenol,allantoin,hyaluronic acid,centella asiatica

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Asiaticoside's mechanism of wound healing involves release of aglycone asiatic acid after hydrolysis by skin beta-glucosidases. the glycoside form provides better stratum corneum penetration than the hydrophobic aglycone, acting as a prodrug for the active asiatic acid at the wound healing site.

Last Verified: Cosing database,bylka et al. centella asiatica review

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides silicone-characteristic silky feel and skin protection with adjustable viscosity.

Why It's Used: The benchmark cosmetic silicone – sets the gold standard for silky application feel, spreadability, and skin protection in virtually all skin care categories.

How It Works: Polydimethylsiloxane chain flexibility provides extremely low surface tension and high spreadability. inert si-o backbone provides chemical stability and excellent skin tolerance. occlusive film formation reduces tewl. higher viscosity grades provide more intense conditioning.

Typically Found In: Moisturizers,foundations,primers,sunscreens – nearly universal

TECHNICAL DETAILS

Primary Category: Functional ingredient – polydimethylsiloxane

Secondary Functions: Barrier sealing,softening

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–30%

SOURCING & ETHICS

Vegan Status: Yes – synthetic

Halal Status: Yes

Source Notes: Plant-derived, synthetic or animal-derived. verify source.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 1/5 – low; formulation-dependent

Sensitivity Concerns: Non-irritating.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Humectants,ceramides,actives as carrier

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Dimethicone's exceptional silky feel arises from its very low intermolecular attractive forces (weak van der waals forces due to non-polar methyl groups) that allow silicone chains to slide freely over skin. the coefficient of kinetic friction for pdms against skin (~0.04) is among the lowest of any cosmetic material – explaining why even small amounts transform product feel.

Last Verified: Cosing database,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Creates a smooth, silky skin feel, reduces friction, and forms a breathable film on skin that enhances product application and wear.

Why It's Used: Silicones provide unmatched aesthetic elegance, thermal stability, and formulation flexibility that enhance both consumer experience and product performance.

How It Works: Siloxane backbone provides a flexible, chemically inert polymer that forms thin, breathable films on skin surface, filling surface irregularities and providing low surface energy for exceptional slip and spreadability.

Typically Found In: Moisturizers,primers,foundations,sunscreens,hair products

TECHNICAL DETAILS

Primary Category: Silicones

Secondary Functions: Emollient,film former

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.5–30%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Synthetic silicone polymer; not plant-derived but generally considered vegan.

SKIN COMPATIBILITY

Irritancy Rating: 1

Comedogenicity Rating: 0

Sensitivity Concerns: Low sensitization potential at recommended use concentrations.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Well-characterized cosmetic ingredient with established safety profile. generally non-irritating at typical use concentrations. suitable for leave-on and rinse-off cosmetics.

Works Well With: Other emollients,uv filters,pigments

Avoid Combining With: Silicone-sensitive formulations; biodegradability concerns in eco-formulations

SCIENTIFIC NOTE

Silicone polymers are poly(dimethylsiloxane) backbones with si-o bond energy (105 kcal/mol) significantly higher than c-c (83 kcal/mol), providing exceptional thermal and oxidative stability. the low surface energy (21 mn/m vs 30+ mn/m for organic polymers) accounts for silicone's unique slip feel, and the si-o bond's flexibility (rotation barrier ~0.3 kcal/mol) enables fluid behavior across wide temperature ranges.

Last Verified: Cosing eu database; pcpc cosmetic ingredient safety reviews; ingredient-specific safety and efficacy literature

Primary Sources: 2025-01-15

DESCRIPTION

What It Does: Provides biocompatible penetration enhancement for improved active ingredient delivery.

Why It's Used: Biocompatible penetration enhancer from renewable sorbitol — dmi provides penetration enhancement without the toxicity of oleic acid or conventional chemical penetration enhancers.

How It Works: Cyclic ether from sorbitol is biocompatible and biodegradable. disrupts stratum corneum lipid packing via ether oxygen hydrogen bonding. solubilises challenging actives (retinoids, salicylic acid, ahas). enhances penetration 2–5× vs equivalent concentrations without dmi.

Typically Found In: Active delivery formulas,penetration-enhanced products,retinoid vehicles

TECHNICAL DETAILS

Primary Category: Functional ingredient – penetration-enhancing solvent

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%–20%

SOURCING & ETHICS

Vegan Status: Yes – from sorbitol (corn or wheat derived)

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Dmi's penetration enhancement mechanism differs from oleic acid's lipid disruption: dmi hydrogen bonds to stratum corneum proteins and lipids, temporarily creating more permeable protein-lipid domains without the membrane-fluidisation that causes oleic acid's irritation. this protein-hydrogen-bonding mechanism provides penetration enhancement from a different, gentler pathway.

Last Verified: Cosing database,croda arlasolve dmi technical data,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Delivers characteristic cosmetic function — skin conditioning, antioxidant protection, active biological benefit, or formulation function — at recommended use concentration.

Why It's Used: Selected for functional contribution and formulation compatibility supported by cosmetic science and regulatory safety data.

How It Works: Works through the mechanism of its molecular class — physicochemical or biological interaction with skin proteins, lipids, or receptors as documented in peer-reviewed cosmetic literature.

Typically Found In: Skin care formulations

TECHNICAL DETAILS

Primary Category: Active ingredient – cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–10%

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Hexylresorcinol has an established safety and efficacy profile within the cosmetic regulatory framework at standard use concentrations.

Last Verified: Cosing database,hexylresorcinol technical literature

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Stimulates fibroblast collagen synthesis via tgf-β1/smad pathway, inhibits nf-kb for anti-inflammatory activity, promotes keratinocyte migration for wound healing, and provides the anti-scarring benefit documented in hypertrophic scar clinical studies.

Why It's Used: Provides the active principle responsible for centella's clinical efficacy in higher concentration and with better batch consistency than whole extract — enabling accurate dosing and stronger label claim substantiation.

How It Works: Madecassoside (and its aglycone madecassic acid) inhibits nf-kb nuclear translocation by blocking ikbα phosphorylation (ic₅₀ ~5 μm), reducing tnf-α and il-1β production. asiaticoside undergoes esterase hydrolysis to asiatic acid which activates tgf-β1 → smad2/3 phosphorylation → col1a1 upregulation.

Typically Found In: Cica skin care,wound healing,anti-scar

TECHNICAL DETAILS

Primary Category: Active ingredient – antioxidant

Secondary Functions: Free radical scavenging,anti-aging

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.01%–1%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Plant-derived extract or synthetic.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; well-tolerated.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Centella triterpenoid clinical evidence includes a double-blind rct showing 65% reduction in stretch mark formation in pregnant women — one of the strongest single-compound botanical anti-scar clinical evidence records.

Last Verified: Cosing database,centella triterpenoid clinical wound healing review

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Delivers characteristic cosmetic function at recommended use concentration.

Why It's Used: Selected for functional contribution and formulation compatibility supported by cosmetic science and regulatory safety data.

How It Works: Works through the mechanism of its molecular class — physicochemical or biological interaction with skin proteins, lipids, or receptors as documented in peer-reviewed cosmetic literature.

Typically Found In: Skin care formulations

TECHNICAL DETAILS

Primary Category: Active ingredient – cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–10%

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Polysilicone-11 has an established safety and efficacy profile within the cosmetic regulatory framework at standard use concentrations.

Last Verified: Cosing database,polysilicone-11 technical literature

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Delivers characteristic cosmetic function at recommended use concentration.

Why It's Used: Selected for functional contribution and formulation compatibility supported by cosmetic science and regulatory safety data.

How It Works: Works through the mechanism of its molecular class — physicochemical or biological interaction with skin proteins, lipids, or receptors as documented in peer-reviewed cosmetic literature.

Typically Found In: Skin care formulations

TECHNICAL DETAILS

Primary Category: Active ingredient – cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–10%

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Silica has an established safety and efficacy profile within the cosmetic regulatory framework at standard use concentrations.

Last Verified: Cosing database,silica technical literature

Primary Sources: 2026-03-12