
Highlights
WHAT IS IT?
Anti-Aging Cream with multiple key ingredients
FEATURES
Brightens complexion, reduces wrinkles, improves skin firmness and elasticity, regenerates skin
BEST FOR
sensitive
CHECKS
Paraben, Preservative
Who Is It For?
What Does It Help With?
Aging Signs Wrinkles Contour Definition Skin BrightnessBudget
Professional (over $150)How To Use
Which routine should it be used in?
Instructions:
Key Information
What L'Occitane Says
Product Description:
This refill is designed to fit perfectly into your existing Harmonie Divine Cream jar. For the very first time, L'Occitane has combined the power of the earth and the sea of Corsica at the heart of a cream with a new sensoriality. Immortelle Millésimée, the flower that never fades, melds together with Jania Rubens - the red algae with the ability to eternally regenerate. L'Occitane has drawn on the extraordinary powers of regeneration of its two precious extracts and integrated them into a youth ritual that offers targeted action to fight the visible effects of time on both the skin and the harmony of the face. Benefits include: Your complexion looks bright and luminous, the appearance of wrinkles is visibly reduced, and radiant and serene, your face reveals a new harmony. Millesimée extract is a superior-quality essential oil with a unique concentration. Organic Immortelle Millésimée essential oil when combined with the Harmonie Divine Serum, 92% consumers reveal skin's texture feels refined. Ideal for wrinkles looking visibly reduced, defining the look of contours, and brightening your complexion. About the Range: Harmonie Divine - Where land and sea meet, an eternal beauty is born. With Harmonie Divine, L'Occitane unveils a skincare line harnessing the fusion of two precious ingredients with exceptional properties: Immortelle Millésimée - the flower that never fades, even more precious - and Jania Rubens - the red algae with the ability to eternally regenerate.
About the Brand:
Ingredients Overview
Ingredients List
Aqua-Water,Coco-Caprylate-Caprate,Caprylic-Capric-Triglyceride,Glycerin,Dicaprylyl-Ether,Cetyl-Palmitate,Oenothera-Biennis-Evening-Primrose-Oil,Dimethicone,Cetearyl-Alcohol,Tapioca-Starch,Ascorbyl-Glucoside,Cetyl-Alcohol,Glyceryl-Stearate,Camelina-Sativa-Seed-Oil,Hydroxyethyl-Acrylate-Sodium-Acryloyldimethyl-Taurate-Copolymer,Borago-Officinalis-Seed-Oil,Helianthus-Annuus-Sunflower-Seed-Oil,Mel-Honey,Helichrysum-Italicum-Flower-Oil,Echium-Plantagineum-Seed-Oil,Jania-Rubens-Extract,Myrtus-Communis-Oil,Hyaluronic-Acid,Helichrysum-Italicum-Extract,Cetearyl-Glucoside,Polysorbate-60,Silica,Palmitic-Acid,Dipotassium-Glycyrrhizate,Peg-100-Stearate,Sucrose-Palmitate,Butylene-Glycol,Phenoxyethanol,Sodium-Citrate,Chlorphenesin,Sodium-Hyaluronate,Sodium-Hydroxide,Ethylhexylglycerin,Glyceryl-Linoleate,Stearic-Acid,Tocopheryl-Acetate,Disodium-Edta,Sorbitan-Isostearate,Adenosine,Carbomer,Magnesium-Aspartate,Zinc-Gluconate,Citric-Acid,Polysorbate-20,Potassium-Sorbate,Copper-Gluconate,Palmitoyl-Oligopeptide,Sodium-Benzoate,Palmitoyl-Tetrapeptide-7,Tocopherol,Parfum-Fragrance,Limonene,Citral,Linalool
Key Ingredients
Organic Immortelle Essential Oil, Organic Onager Oil, Jania Rubens, Hyaluronic Acid
Ingredients Details
Adenosine
Common Name(s): Adenine riboside,9-beta-d-ribofuranosyladenine
CAS Number: 58-61-7
DESCRIPTION
What It Does: Reduces fine lines, stimulates collagen, firms skin, and reduces inflammation.
Why It's Used: Fda-recognized anti-wrinkle active with multi-action collagen stimulation + wrinkle reduction + anti-inflammatory efficacy.
How It Works: Activates adenosine a2a receptors on fibroblasts stimulating collagen type i. also activates pka pathway promoting atp production and reducing inflammatory cytokines.
Typically Found In: Anti-aging serums,wrinkle treatments,korean skincare
TECHNICAL DETAILS
Primary Category: Active ingredient – purine nucleoside / anti-aging
Secondary Functions: Collagen stimulation,anti-inflammatory,cell energy
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.04%–0.1%
SOURCING & ETHICS
Vegan Status: Yes – synthetically produced
Halal Status: Yes
Source Notes: Synthetically produced for cosmetic use.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 0/5 – non-comedogenic
Sensitivity Concerns: Non-irritating; excellent tolerability.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. fda-recognized as safe and effective anti-wrinkle ingredient. ewg score: 1.
Works Well With: Other b vitamins,niacinamide,antioxidant complexes
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
A 2002 clinical study demonstrated 0.04% adenosine cream significantly reduced wrinkle depth and increased skin elasticity after 4 weeks. fda recognition requires controlled clinical trial evidence.
Last Verified: Cosing database,adenosine anti-aging clinical data,fda otc anti-wrinkle monograph
Primary Sources: 2026-03-12
Carbomer
Common Name(s): Carbopol,polyacrylic acid,carboxyvinyl polymer
DESCRIPTION
What It Does: Provides transparent gel textures and thickening at very low concentrations via ph-responsive swelling.
Why It's Used: The most widely used gel thickener – provides crystal-clear, stable gels at concentrations as low as 0.1-0.5% with ph-controlled viscosity.
How It Works: Highly crosslinked polyacrylic acid remains tightly coiled at acidic ph. neutralization with naoh or triethanolamine ionizes carboxylic groups causing electrostatic repulsion that unfolds and swells the polymer coils, dramatically increasing viscosity. concentration-dependent thickening.
Typically Found In: Gels,serums,emulsions,sunscreens
TECHNICAL DETAILS
Primary Category: Functional ingredient – polyacrylic acid thickener
Secondary Functions: Skin conditioning
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%–2%
SOURCING & ETHICS
Vegan Status: Yes – synthetic
Halal Status: Yes
Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 0/5 – non-comedogenic
Sensitivity Concerns: Well-tolerated by most skin types.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.
Works Well With: Standard skincare actives
Avoid Combining With: No known significant incompatibilities
SCIENTIFIC NOTE
Carbomer's ph-responsive swelling mechanism provides an elegant formulation control tool: a neutralized gel can be liquefied by ph reduction (adding acid) and re-thickened by reneutralization. this reversible rheology control allows two-phase products that mix on application without the need for mechanical emulsification.
Last Verified: Cosing database,cir safety assessment
Primary Sources: 2026-03-12
Chlorphenesin
Common Name(s): 3-(4-chlorophenoxy)-1,2-propanediol,globacid
CAS Number: 104-29-0
DESCRIPTION
What It Does: Provides gram-negative focused preservation complementary to phenoxyethanol for comprehensive spectrum coverage.
Why It's Used: Phenoxyethanol complement — chlorphenesin's gram-negative and antifungal coverage complements phenoxyethanol's gram-positive activity for full-spectrum preservation at lower individual concentrations.
How It Works: 4-chlorophenol ether glycol disrupts bacterial and fungal membranes. strong gram-negative activity (pseudomonas, e. coli). good candida antifungal activity. used with phenoxyethanol for synergistic broad-spectrum coverage. ph stable 3-9.
Typically Found In: Comprehensive preservation systems,baby products (low concentration)
TECHNICAL DETAILS
Primary Category: Functional ingredient – glycerol ether preservative
Secondary Functions: Skin conditioning
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%–0.3%
SOURCING & ETHICS
Vegan Status: Yes – synthetic
Halal Status: Yes
Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 0/5 – non-comedogenic
Sensitivity Concerns: Well-tolerated by most skin types.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Eu max 0.3% cosmetics. good safety profile. synergistic combination with phenoxyethanol (0.3% pe + 0.1% chlorphenesin often equivalent to 1% pe alone).
Works Well With: Standard skincare actives
Avoid Combining With: No known significant incompatibilities
SCIENTIFIC NOTE
Chlorphenesin + phenoxyethanol synergy operates through a classic spectrum-filling combination: phenoxyethanol provides strong gram-positive antimicrobial activity while chlorphenesin provides gram-negative and antifungal coverage. the combination's minimum inhibitory concentration sum is subadditive (provides equivalent preservation at combined concentrations below what either alone would require) — textbook pharmacological synergy enabling lower total preservative load.
Last Verified: Cosing database,eu preservative annex v,cir safety assessment
Primary Sources: 2026-03-12
Dimethicone
Common Name(s): Pdms,polydimethylsiloxane,silicone fluid
CAS Number: 9006-65-9
DESCRIPTION
What It Does: Provides silicone-characteristic silky feel and skin protection with adjustable viscosity.
Why It's Used: The benchmark cosmetic silicone – sets the gold standard for silky application feel, spreadability, and skin protection in virtually all skin care categories.
How It Works: Polydimethylsiloxane chain flexibility provides extremely low surface tension and high spreadability. inert si-o backbone provides chemical stability and excellent skin tolerance. occlusive film formation reduces tewl. higher viscosity grades provide more intense conditioning.
Typically Found In: Moisturizers,foundations,primers,sunscreens – nearly universal
TECHNICAL DETAILS
Primary Category: Functional ingredient – polydimethylsiloxane
Secondary Functions: Barrier sealing,softening
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%–30%
SOURCING & ETHICS
Vegan Status: Yes – synthetic
Halal Status: Yes
Source Notes: Plant-derived, synthetic or animal-derived. verify source.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 1/5 – low; formulation-dependent
Sensitivity Concerns: Non-irritating.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Humectants,ceramides,actives as carrier
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Dimethicone's exceptional silky feel arises from its very low intermolecular attractive forces (weak van der waals forces due to non-polar methyl groups) that allow silicone chains to slide freely over skin. the coefficient of kinetic friction for pdms against skin (~0.04) is among the lowest of any cosmetic material – explaining why even small amounts transform product feel.
Last Verified: Cosing database,cir safety assessment
Primary Sources: 2026-03-12