L'Oreal Paris Revitalift Hyaluronic Acid Hydrating Gel Cleanser (100 ml)

DESCRIPTION

What It Does: Reduces fine lines, stimulates collagen, firms skin, and reduces inflammation.

Why It's Used: Fda-recognized anti-wrinkle active with multi-action collagen stimulation + wrinkle reduction + anti-inflammatory efficacy.

How It Works: Activates adenosine a2a receptors on fibroblasts stimulating collagen type i. also activates pka pathway promoting atp production and reducing inflammatory cytokines.

Typically Found In: Anti-aging serums,wrinkle treatments,korean skincare

TECHNICAL DETAILS

Primary Category: Active ingredient – purine nucleoside / anti-aging

Secondary Functions: Collagen stimulation,anti-inflammatory,cell energy

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.04%–0.1%

SOURCING & ETHICS

Vegan Status: Yes – synthetically produced

Halal Status: Yes

Source Notes: Synthetically produced for cosmetic use.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; excellent tolerability.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. fda-recognized as safe and effective anti-wrinkle ingredient. ewg score: 1.

Works Well With: Other b vitamins,niacinamide,antioxidant complexes

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

A 2002 clinical study demonstrated 0.04% adenosine cream significantly reduced wrinkle depth and increased skin elasticity after 4 weeks. fda recognition requires controlled clinical trial evidence.

Last Verified: Cosing database,adenosine anti-aging clinical data,fda otc anti-wrinkle monograph

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides dual fragrance and preservative activity as an aromatic alcohol.

Why It's Used: Multi-function ingredient serving as both fragrance component and preservative – reduces formulation complexity by providing both functions in one ingredient.

How It Works: Phenylcarbinol provides antimicrobial activity via membrane disruption (effective vs gram-positive bacteria and moulds). solvent for fragrances and difficult-to-dissolve actives. mild oxidative conversion to benzaldehyde provides sweet almond-like fragrance.

Typically Found In: Fragrances,preserved cosmetics,solvent systems

TECHNICAL DETAILS

Primary Category: Fragrance component / preservative

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.001%–1% (fragrance); up to 1% as preservative

SOURCING & ETHICS

Vegan Status: Yes – from toluene, or jasmine absolute

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Eu cosmetics regulation: declared fragrance allergen. also listed as approved preservative (annex v, max 1%). dual regulatory status (fragrance + preservative) depending on function and concentration.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Benzyl alcohol's dual regulatory status (fragrance allergen and approved preservative) creates a formulation paradox: it must be listed as a fragrance allergen if present >0.001% (leave-on) regardless of whether it was added for fragrance or preservation. this regulatory dual identity means a preservative added for antimicrobial function triggers the same allergen declaration requirement as a fragrance added for scent.

Last Verified: Cosing database,ifra standards,eu preservative annex v

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides fixative fragrance and solvent properties with anti-mite activity.

Why It's Used: Natural ester fragrance compound occurring in jasmine and ylang ylang providing fixative and solvent benefits in fragranced cosmetics.

How It Works: Ester of benzyl alcohol and benzoic acid. solvent for difficult-to-dissolve fragrance compounds. penetrates insect/mite cuticle for scabicidal activity. mild skin fixative from ester-protein interactions.

Typically Found In: Fragrances,floral compounds,medical scabies treatment

TECHNICAL DETAILS

Primary Category: Fragrance component / scabicide

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.001%–1%

SOURCING & ETHICS

Vegan Status: Yes – from jasmine, ylang ylang, peru balsam

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Eu cosmetics regulation: declared fragrance allergen. ifra guidelines apply.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Benzyl benzoate's natural occurrence in jasmine absolute (up to 6%) means that products containing jasmine absolute naturally contain benzyl benzoate as a declared fragrance allergen – regardless of whether the formulator intentionally added it. this highlights how natural ingredients can automatically generate regulatory allergen declarations.

Last Verified: Cosing database,ifra standards

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides floral-balsamic scent with uv-absorbing fixative properties.

Why It's Used: Natural jasmine-associated fragrance ester with mild uv protection contribution for fragranced sun-exposed products.

How It Works: Salicylate ester absorbs uv-b mildly. provides fixative function by slowing evaporation of lighter fragrance top notes. naturally in jasmine absolute (1-3%). good skin absorption.

Typically Found In: Floral fragrances,sun-exposed products

TECHNICAL DETAILS

Primary Category: Fragrance component – floral fixative

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.001%–1%

SOURCING & ETHICS

Vegan Status: Yes – from jasmine absolute, or synthetic

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Eu cosmetics regulation: declared fragrance allergen. ifra guidelines apply.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Benzyl salicylate's salicylate moiety provides uv absorption in the uvb range (absorbs at 295-315nm) despite not being a registered uv filter. its occurrence in jasmine absolute means natural jasmine-fragranced products inherently contain a mild uv absorber – an incidental benefit of the natural fragrance chemistry that wasn't intentionally designed as photoprotection.

Last Verified: Cosing database,ifra standards

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides the most potent antimicrobial diol activity alongside skin feel enhancement.

Why It's Used: Premium antimicrobial diol — caprylyl glycol's c8 chain provides the strongest membrane-disrupting antimicrobial activity of common diol preservative boosters with unique skin-feel enhancement.

How It Works: C8 1,2-diol: c8 chain length provides strongest bacterial and fungal membrane disruption of common diols. emollient skin feel improvement from c8 chain length interaction with skin surface. active at lower concentrations than shorter-chain diols. synergistic with ethylhexylglycerin.

Typically Found In: Natural preservation systems,skin feel enhancement

TECHNICAL DETAILS

Primary Category: Functional ingredient – antimicrobial humectant

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–1%

SOURCING & ETHICS

Vegan Status: Yes – synthetic

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Caprylyl glycol's antimicrobial potency follows the chain-length dependent membrane activity of fatty acids: c8 is the optimal chain length for membrane disruption (same as caprylic acid's antimicrobial optimum), providing maximum membrane integration without the skin sensitisation associated with longer chain lengths. this chain-length pharmacophore relationship is why c8 > c6 > c5 in diol antimicrobial potency despite identical head group chemistry.

Last Verified: Cosing database,schülke sensiva sc 50 technical data,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Delivers targeted skin-conditioning or bioactive benefits through a specific mechanism of action suited to the formulation's intended purpose.

Why It's Used: Specialty actives address specific skin concerns through targeted molecular mechanisms, providing efficacy beyond what base formulation ingredients alone can achieve.

How It Works: The bioactive compound interacts with specific molecular targets in skin cells or the extracellular matrix — enzymes, receptors, structural proteins, or signaling molecules — triggering beneficial biological responses.

Typically Found In: Serums,treatments,moisturizers,specialty products

TECHNICAL DETAILS

Primary Category: Specialty actives

Secondary Functions: Skin-conditioning,anti-aging

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.01–5%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Specialty active ingredient; check individual sourcing for vegan status.

SKIN COMPATIBILITY

Irritancy Rating: 1

Comedogenicity Rating: 0

Sensitivity Concerns: Low sensitization potential at recommended use concentrations.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Well-characterized cosmetic ingredient with established safety profile. generally non-irritating at typical use concentrations. suitable for leave-on and rinse-off cosmetics.

Works Well With: Niacinamide,hyaluronic acid,vitamin c,peptides

Avoid Combining With: Incompatible with oxidizing agents; check ph stability

SCIENTIFIC NOTE

Specialty actives typically work through enzyme inhibition (e.g., tyrosinase inhibition for brightening, mmp inhibition for anti-aging), receptor activation (e.g., retinoid receptors, ppar-γ for barrier genes), or transcription factor modulation (e.g., nrf2 for antioxidant gene upregulation). structure-activity relationships determine potency and selectivity.

Last Verified: Cosing eu database; pcpc cosmetic ingredient safety reviews; ingredient-specific safety and efficacy literature

Primary Sources: 2025-01-15

DESCRIPTION

What It Does: Provides soft, lasting rose-floral fragrance note.

Why It's Used: Essential rose fragrance monoterpene for lasting smooth floral notes in high-quality perfumery and cosmetic fragrances.

How It Works: Allylic alcohol monoterpene provides fixative property in fragrance blends. good skin substantivity for lasting scent. softer, rounder rose note vs geraniol's fresher character. natural in rose otto at 18-34%.

Typically Found In: Rose perfumes,floral fragrances,luxury skincare

TECHNICAL DETAILS

Primary Category: Fragrance component – monoterpene alcohol

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.001%–1%

SOURCING & ETHICS

Vegan Status: Yes – from rose, geranium, citronella oils

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Eu cosmetics regulation: declared fragrance allergen. ifra guidelines apply.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Citronellol's r-enantiomer (natural) vs s-enantiomer (synthetic) provide meaningfully different scent character – a remarkable demonstration of chiral scent discrimination by olfactory receptors. the (r) form provides the characteristic rose note while the (s) form has a distinctly different, less pleasant character. this enantiomeric scent difference means that the biological handedness of naturally-sourced vs racemic synthetic citronellol produces perceptibly different fragrance quality.

Last Verified: Cosing database,ifra standards

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides silicone-characteristic silky feel and skin protection with adjustable viscosity.

Why It's Used: The benchmark cosmetic silicone – sets the gold standard for silky application feel, spreadability, and skin protection in virtually all skin care categories.

How It Works: Polydimethylsiloxane chain flexibility provides extremely low surface tension and high spreadability. inert si-o backbone provides chemical stability and excellent skin tolerance. occlusive film formation reduces tewl. higher viscosity grades provide more intense conditioning.

Typically Found In: Moisturizers,foundations,primers,sunscreens – nearly universal

TECHNICAL DETAILS

Primary Category: Functional ingredient – polydimethylsiloxane

Secondary Functions: Barrier sealing,softening

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–30%

SOURCING & ETHICS

Vegan Status: Yes – synthetic

Halal Status: Yes

Source Notes: Plant-derived, synthetic or animal-derived. verify source.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 1/5 – low; formulation-dependent

Sensitivity Concerns: Non-irritating.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Humectants,ceramides,actives as carrier

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Dimethicone's exceptional silky feel arises from its very low intermolecular attractive forces (weak van der waals forces due to non-polar methyl groups) that allow silicone chains to slide freely over skin. the coefficient of kinetic friction for pdms against skin (~0.04) is among the lowest of any cosmetic material – explaining why even small amounts transform product feel.

Last Verified: Cosing database,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Attracts water molecules from the environment and deeper skin layers to the stratum corneum, maintaining surface hydration and suppleness.

Why It's Used: Humectants address the most common skin concern — dryness — by providing immediate and sustained moisture delivery to the stratum corneum.

How It Works: Multiple hydroxyl or other polar groups form hydrogen bonds with water molecules, physically trapping water in the stratum corneum while creating an osmotic driving force for water migration from deeper skin layers.

Typically Found In: Serums,moisturizers,toners,essences,masks

TECHNICAL DETAILS

Primary Category: Humectants

Secondary Functions: Humectant,skin-conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.5–20%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Synthetic or plant-derived humectant; no animal components.

SKIN COMPATIBILITY

Irritancy Rating: 1

Comedogenicity Rating: 0

Sensitivity Concerns: Low sensitization potential at recommended use concentrations.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Well-characterized cosmetic ingredient with established safety profile. generally non-irritating at typical use concentrations. suitable for leave-on and rinse-off cosmetics.

Works Well With: Ceramides,other humectants,emollients,occlusives

Avoid Combining With: Very low humidity environments without occlusive layer

SCIENTIFIC NOTE

Humectant efficacy correlates with hygroscopic capacity (g water per g humectant at standard rh). glycerin absorbs ~0.83 g water/g at 90% rh; hyaluronic acid retains up to 1000× its weight in water through the polyelectrolyte expansion of its carboxylate groups. optimal formulations balance humectants with occlusives (waxes, silicones) to prevent transepidermal water loss.

Last Verified: Cosing eu database; pcpc cosmetic ingredient safety reviews; ingredient-specific safety and efficacy literature

Primary Sources: 2025-01-15

DESCRIPTION

What It Does: Provides glycyrrhizic acid anti-inflammatory and cortisol-potentiating soothing activity.

Why It's Used: The anti-inflammatory licorice active — dipotassium glycyrrhizate provides stronger anti-inflammatory activity than glabridin-containing licorice extract, making it the preferred licorice active for anti-inflammatory formulations.

How It Works: Glycyrrhizic acid inhibits 11-beta-hsd (11-beta-hydroxysteroid dehydrogenase) which inactivates cortisol to cortisone. local cortisol levels increase providing anti-inflammatory activity analogous to mild topical corticosteroid. also inhibits phospholipase a2 and prostaglandin synthesis directly.

Typically Found In: Sensitive skin serums,anti-inflammatory products,anti-itch formulas

TECHNICAL DETAILS

Primary Category: Active ingredient – anti-inflammatory licorice

Secondary Functions: Redness reduction,anti-inflammatory,calming

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–1%

SOURCING & ETHICS

Vegan Status: Yes – from glycyrrhiza glabra root

Halal Status: Yes

Source Notes: Plant-derived extract or synthetic.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; ideal for reactive and sensitive skin.

Safe for Sensitive Skin: Yes – particularly recommended for sensitive skin

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Ceramides,panthenol,allantoin,hyaluronic acid,centella asiatica

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Dipotassium glycyrrhizate's 11-beta-hsd inhibition provides a corticosteroid-potentiating mechanism: by preventing cortisol deactivation to cortisone, it effectively amplifies the anti-inflammatory activity of the skin's own naturally produced glucocorticoid without introducing exogenous steroids — providing a 'natural steroid potentiation' that explains why licorice preparations have been used as a topical anti-inflammatory for millennia.

Last Verified: Cosing database,armanini et al. glycyrrhizate review

Primary Sources: 2026-03-12