Matrixyl 10% + HA

The Ordinary

Matrixyl 10% + HA

Matrixyl 10% + HA

The Ordinary

matrixyl-10-ha

Serum

9784784191781

Morning or Evening?

Morning
Evening
Both

How often will you use this product?

Everyday
Every other day
Every 3 days
Every 4 days
Every 5 days
Every 6 days
Once a week
Twice a week
On specific days
As needed
On rotation

Notes

Add to Routine
Compare with Similar

Compatibility Score

0%

Microbiome
Ingredients
Biological
Environment
Lifestyle

How It Fits Into Your Skincare Routine

Login to see compatibility score and learn how this works with your skin.

Highlights

WHAT IS IT?

Peptide serum with Matrixyl 10% concentration

FEATURES

Targets fine lines and wrinkles, Promotes firmer and plumper skin, Supports collagen production

BEST FOR

normal

CHECKS

Water-based, Alcohol-free, Oil-free, Silicone-free

Who Is It For?

Adults Concerned With Signs Of Aging

What Does It Help With?

Fine Lines Wrinkles Skin Firmness Skin Plumping

Budget

Affordable (under $30)

How To Use

Which routine should it be used in?

Morning
Evening
 
Cleanse
Tone
Eyecare
Serum
Moisturize
Suncare
 

Instructions:

Apply a few drops to the face in the morning and evening

Key Information

Vegan
Cruelty-free
Sensitive-safe
Non-comedogenic
Hypoallergenic
Microbiome-safe
Preservative-free
Eco-friendly
Pregnancy-safe
Oil-free

What The Ordinary Says

Product Description:

A skin-firming serum that targets fine lines and wrinkles by promoting firmer, plumper skin. With two generations of MatrixylTM and hyaluronic acid, this lightweight serum improves the appearance of facial areas prone to fine lines by supporting your skin's overall collagen production.

About the Brand:

Revolutionizing skincare transparency, The Ordinary offers clinical formulations with established technologies at radical price points. Founded by Brandon Truaxe under DECIEM in 2016, this disruptive brand focuses on single-ingredient integrity and scientific communication. Experience advanced actives without marketing hype or inflated costs through straightforward formulations that democratize effective skincare.

Ingredients Overview

Ingredients List

Aqua,Glycerin,Butylene-Glycol,Palmitoyl-Tripeptide-1,Palmitoyl-Tetrapeptide-7,Palmitoyl-Tripeptide-38,Sodium-Hyaluronate,Hydroxypropyl-Cyclodextrin,PPG-26-Buteth-26,PEG-40-Hydrogenated-Castor-Oil,Polyacrylate-Crosspolymer-6,Trisodium-Ethylenediamine-Disuccinate,Carbomer,Polysorbate-20,Ethoxydiglycol,Phenoxyethanol,Chlorphenesin

Key Ingredients

Matrixyl, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-38, Sodium Hyaluronate

Ingredients Details

Butylene Glycol

Common Name(s): 1,3-butanediol,bg,1,3-butylene glycol

CAS Number: 107-88-0

DESCRIPTION

What It Does: Provides humectant hydration and active ingredient solubilization with excellent skin feel.

Why It's Used: Preferred glycol humectant in premium and k-beauty formulations for superior skin feel vs propylene glycol with equivalent functionality.

How It Works: Two hydroxyl groups at 1,3-positions provide water binding and solvent activity. better tolerated than propylene glycol with minimal sensitization risk. 4-carbon backbone provides slightly greater hydrophobic character enabling dissolution of less polar actives vs pg.

Typically Found In: Toners,essences,serums,k-beauty formulas

TECHNICAL DETAILS

Primary Category: Functional ingredient โ€“ glycol humectant

Secondary Functions: Tewl reduction,skin plumping

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%โ€“10%

SOURCING & ETHICS

Vegan Status: Yes โ€“ synthetic

Halal Status: Yes

Source Notes: Synthetic or naturally derived. excellent aqueous solubility.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Non-irritating; suitable for all skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Ceramides,emollients,occlusives,glycerin,hyaluronic acid

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

K-beauty's preference for butylene glycol over propylene glycol is driven by two factors: bg's superior skin feel (less tacky than pg's higher viscosity) and its lower sensitization potential (1,3-bg has better spatial distribution of hydroxyl groups that reduces protein interaction vs pg's 1,2-position oh groups).

Last Verified: Cosing database,cir safety assessment

Primary Sources: 2026-03-12

Glycerin

Common Name(s): Glycerol,glycerine,1,2,3-propanetriol

CAS Number: 56-81-5

DESCRIPTION

What It Does: Glycerin pulls water from the environment and deeper skin layers into the outer skin layer (epidermis), boosting moisture levels and keeping skin soft, smooth, and plump.

Why It's Used: It is used in virtually every moisturizer, serum, and cleanser because it is highly effective at hydrating skin, is well-tolerated by all skin types, and enhances the texture and spreadability of formulations.

How It Works: As a humectant, glycerin forms hydrogen bonds with water molecules, trapping them in the skin. it also reinforces the skin barrier by integrating into lipid structures between skin cells.

Typically Found In: Moisturizers,serums,cleansers,toners,sheet masks,sunscreens,body lotions,shampoos,conditioners

TECHNICAL DETAILS

Primary Category: Humectant

Secondary Functions: Skin barrier support,emollient,solvent

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%โ€“30% (typical: 3โ€“10%)

SOURCING & ETHICS

Vegan Status: Yes โ€“ plant-derived (coconut, soy, palm) or synthetic

Halal Status: Yes โ€“ when plant-derived or synthetic; verify source with supplier

Source Notes: Derived from plant oils via hydrolysis or saponification; synthetic versions also available. palm-derived glycerin carries sustainability concerns.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low; non-irritating at all standard concentrations

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Extremely rare allergic reactions; generally safe for all skin types including sensitive and baby skin

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Widely recognized as safe. ewg hazard score: 1. no significant concerns for irritation, sensitization, or toxicity at typical concentrations (up to 50%).

Works Well With: Hyaluronic acid,ceramides,niacinamide,panthenol,urea,peptides,retinol,ahas/bhas

Avoid Combining With: No known incompatibilities at standard concentrations

SCIENTIFIC NOTE

Glycerin is an endogenous skin component found naturally in the stratum corneum. aquaporin-3 channels in keratinocytes facilitate glycerin transport, making it integral to natural skin hydration pathways.

Last Verified: Cosing database,cir safety assessment,ewg skin deep,inci decoder

Primary Sources: 2026-03-12

Hydroxypropyl Cyclodextrin

Common Name(s): Hydroxypropyl cyclodextrin,cosmetic active,functional ingredient

CAS Number: N/a

DESCRIPTION

What It Does: Delivers characteristic cosmetic function at recommended use concentration.

Why It's Used: Selected for functional contribution and formulation compatibility supported by cosmetic science and regulatory safety data.

How It Works: Works through the mechanism of its molecular class โ€” physicochemical or biological interaction with skin proteins, lipids, or receptors as documented in peer-reviewed cosmetic literature.

Typically Found In: Skin care formulations

TECHNICAL DETAILS

Primary Category: Active ingredient โ€“ cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%โ€“10%

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1โ€“2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Hydroxypropyl cyclodextrin has an established safety and efficacy profile within the cosmetic regulatory framework at standard use concentrations.

Last Verified: Cosing database,hydroxypropyl cyclodextrin technical literature

Primary Sources: 2026-03-12

Palmitoyl Tetrapeptide-7

Common Name(s): Pal-gqpr,matrixyl 3000 component,palmitoyl gly-gln-pro-arg

CAS Number: N/a

DESCRIPTION

What It Does: Reduces inflammatory cytokine il-6, calms skin inflammation, and stimulates ecm components for anti-aging.

Why It's Used: Used as the anti-inflammatory component of matrixyl 3000 for complementary anti-aging via inflammation-driven aging pathway inhibition.

How It Works: Pal-gqpr mimics immunomodulatory beta-msh peptide. binds mc receptors reducing il-6, a pro-aging inflammatory cytokine that inhibits collagen synthesis. works synergistically with pal-kttks in matrixyl 3000.

Typically Found In: Anti-aging serums,anti-inflammatory formulations,redness relief with anti-aging benefits

TECHNICAL DETAILS

Primary Category: Active ingredient โ€“ anti-inflammatory signal peptide

Secondary Functions: Il-6 reduction,anti-inflammatory signaling

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 50โ€“1000 ppm

SOURCING & ETHICS

Vegan Status: Yes โ€“ synthetically produced

Halal Status: Yes

Source Notes: Synthesized by spps with palmitoyl esterification. commercially supplied as matrixyl 3000 with pal-kttks (sederma).

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Non-irritating; suitable for all skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Exceptional safety profile. ewg score: 1.

Works Well With: Hyaluronic acid,ceramides,retinol,vitamin c,niacinamide

Avoid Combining With: Avoid mixing with high-concentration ahas at same ph (may hydrolyze peptide bonds)

SCIENTIFIC NOTE

The pal-kttks + pal-gqpr combination in matrixyl 3000 addresses two complementary aging pathways simultaneously: collagen stimulation (pal-kttks) and inflammation-driven collagen suppression reduction (pal-gqpr), providing superior anti-aging efficacy vs either peptide alone.

Last Verified: Cosing database,sederma matrixyl 3000 technical data,gorouhi & maibach peptide review

Primary Sources: 2026-03-12