
Highlights
WHAT IS IT?
Barrier recovery serum with multiple active ingredients
FEATURES
Encourages barrier repair, improves skin texture, repairs visible skin damage, suitable for all skin types, powered with Matrixyl 3000
BEST FOR
sensitive
CHECKS
Do not store above 25ยฐC, For external use only, Avoid direct contact with eyes, Contains no mentioned harsh preservatives or allergens
Who Is It For?
All Genders All Ages (not Specified)What Does It Help With?
Barrier Repair Skin Texture Improvement Visible Skin Damage RepairBudget
Mid-range ($30-$75)How To Use
Which routine should it be used in?
Instructions:
Key Information
What NATURES PALETTE Says
Product Description:
This serum is powered with Matrixyl 3000 to encourage barrier repair and improve skin texture while repairing visible skin damage. Peptica Barrier Recovery Serum. This product is suitable for all skin types and focuses on barrier repairing for a healthy, glowy skin.
About the Brand:
Ingredients Overview
Ingredients List
Aqua, Propylene-Glycol, Glycerin, Butylene-Glycol, Propanediol, Dipropylene-Glycol, Sodium-Hyaluronate, Hydroxyacetophenone, Caprylyl-Glycol, Acrylates/C10-30-Alkyl-Acrylate-Crosspolymer, Triethanolamine, Sodium-Lauroyl-Lactylate, Centella-Asiatica-Extract, Tetrasodium-EDTA, Pyrus-Malus-(Apple)-Fruit-Extract, Vitis-Vinifera-(Grape)-Fruit-Extract, Scutellaria-Baicalensis-Root-Extract, Polygonum-Cuspidatum-Root-Extract, Camellia-Sinensis-Leaf-Extract, Glycyrrhiza-Glabra-(Licorice)-Root-Extract, Carbomer, Ceramide-NP, Magnesium-Carboxymethyl-Beta-Glucan, Chamomilla-Recutita-(Matricaria)-Flower-Extract, Rosmarinus-Officinalis-(Rosemary)-Leaf-Extract, Ceramide-AP, Phytosphingosine, Cholesterol, Polysorbate-20, Xanthan-Gum, Dipotassium-Glycyrrhizate, Acetyl-Hexapeptide-8, Palmitoyl-Tripeptide-1, Palmitoyl-Tetrapeptide-7, Ceramide-EOP
Key Ingredients
Matrixyl 3000 (Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7), Ceramide NP, Sodium Hyaluronate
Ingredients Details
Carbomer
Common Name(s): Carbopol,polyacrylic acid,carboxyvinyl polymer
DESCRIPTION
What It Does: Provides transparent gel textures and thickening at very low concentrations via ph-responsive swelling.
Why It's Used: The most widely used gel thickener โ provides crystal-clear, stable gels at concentrations as low as 0.1-0.5% with ph-controlled viscosity.
How It Works: Highly crosslinked polyacrylic acid remains tightly coiled at acidic ph. neutralization with naoh or triethanolamine ionizes carboxylic groups causing electrostatic repulsion that unfolds and swells the polymer coils, dramatically increasing viscosity. concentration-dependent thickening.
Typically Found In: Gels,serums,emulsions,sunscreens
TECHNICAL DETAILS
Primary Category: Functional ingredient โ polyacrylic acid thickener
Secondary Functions: Skin conditioning
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%โ2%
SOURCING & ETHICS
Vegan Status: Yes โ synthetic
Halal Status: Yes
Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Well-tolerated by most skin types.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Good safety profile at recommended concentrations. ewg score: 1โ2.
Works Well With: Standard skincare actives
Avoid Combining With: No known significant incompatibilities
SCIENTIFIC NOTE
Carbomer's ph-responsive swelling mechanism provides an elegant formulation control tool: a neutralized gel can be liquefied by ph reduction (adding acid) and re-thickened by reneutralization. this reversible rheology control allows two-phase products that mix on application without the need for mechanical emulsification.
Last Verified: Cosing database,cir safety assessment
Primary Sources: 2026-03-12
Cholesterol
Common Name(s): 5-cholesten-3-ol,cholesterin
CAS Number: 57-88-5
DESCRIPTION
What It Does: Provides essential barrier sterol function as one of three critical stratum corneum lipid components.
Why It's Used: Essential component of complete barrier repair formulations โ the stratum corneum barrier requires ceramides:cholesterol:fatty acids in approximately 1:1:1 molar ratio for complete barrier restoration.
How It Works: Integrates between ceramide headgroups in lamellar body structures, providing fluidity and flexibility to the otherwise rigid ceramide-dominated lipid matrix. controls lamellar body phase behavior for functional barrier.
Typically Found In: Barrier repair moisturizers,eczema treatments,dry skin formulations
TECHNICAL DETAILS
Primary Category: Active ingredient โ barrier sterol
Secondary Functions: Lamellar body structure,barrier sterol
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.01%โ1%
SOURCING & ETHICS
Vegan Status: Conditional โ animal-derived (lanolin) or plant-derived phytosterol analogs; verify
Halal Status: Conditional โ verify source
Source Notes: Traditionally from lanolin (wool grease). plant-derived cholesterol alternatives include phytosterols, though these show slightly different barrier integration. verify for vegan/halal.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Endogenous molecule; excellent tolerability.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Exceptional safety profile. natural skin component. ewg score: 1.
Works Well With: Other ceramides,cholesterol,free fatty acids,hyaluronic acid,niacinamide
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Elias demonstrated that barrier repair requires all three lipid classes (ceramides, cholesterol, fatty acids) in approximately equimolar ratios. formulations providing only ceramides without cholesterol and fatty acids show significantly inferior barrier restoration vs complete triple-lipid combinations.
Last Verified: Cosing database,elias et al. barrier lipid ratio study,loden barrier repair review
Primary Sources: 2026-03-12
Glycerin
Common Name(s): Glycerol,glycerine,1,2,3-propanetriol
CAS Number: 56-81-5
DESCRIPTION
What It Does: Glycerin pulls water from the environment and deeper skin layers into the outer skin layer (epidermis), boosting moisture levels and keeping skin soft, smooth, and plump.
Why It's Used: It is used in virtually every moisturizer, serum, and cleanser because it is highly effective at hydrating skin, is well-tolerated by all skin types, and enhances the texture and spreadability of formulations.
How It Works: As a humectant, glycerin forms hydrogen bonds with water molecules, trapping them in the skin. it also reinforces the skin barrier by integrating into lipid structures between skin cells.
Typically Found In: Moisturizers,serums,cleansers,toners,sheet masks,sunscreens,body lotions,shampoos,conditioners
TECHNICAL DETAILS
Primary Category: Humectant
Secondary Functions: Skin barrier support,emollient,solvent
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 1%โ30% (typical: 3โ10%)
SOURCING & ETHICS
Vegan Status: Yes โ plant-derived (coconut, soy, palm) or synthetic
Halal Status: Yes โ when plant-derived or synthetic; verify source with supplier
Source Notes: Derived from plant oils via hydrolysis or saponification; synthetic versions also available. palm-derived glycerin carries sustainability concerns.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low; non-irritating at all standard concentrations
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Extremely rare allergic reactions; generally safe for all skin types including sensitive and baby skin
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Widely recognized as safe. ewg hazard score: 1. no significant concerns for irritation, sensitization, or toxicity at typical concentrations (up to 50%).
Works Well With: Hyaluronic acid,ceramides,niacinamide,panthenol,urea,peptides,retinol,ahas/bhas
Avoid Combining With: No known incompatibilities at standard concentrations
SCIENTIFIC NOTE
Glycerin is an endogenous skin component found naturally in the stratum corneum. aquaporin-3 channels in keratinocytes facilitate glycerin transport, making it integral to natural skin hydration pathways.
Last Verified: Cosing database,cir safety assessment,ewg skin deep,inci decoder
Primary Sources: 2026-03-12
Hydroxyacetophenone
Common Name(s): Para-hydroxyacetophenone,piceol,4-acetylphenol
CAS Number: 99-93-4
DESCRIPTION
What It Does: Provides antioxidant and preservative-boosting activity in a naturally-occurring clean-label phenolic.
Why It's Used: Clean-label preservation support โ hydroxyacetophenone provides antioxidant and antimicrobial-boosting properties from a naturally-occurring compound accepted in natural cosmetic certifications.
How It Works: Para-hydroxyl group provides antioxidant radical scavenging. disrupts bacterial cell membrane penetration for preservative system boosting. anti-inflammatory via nf-kb inhibition. occurs naturally in plants including pear and raspberry as a secondary metabolite.
Typically Found In: Natural preservation systems,antioxidant serums,clean beauty
TECHNICAL DETAILS
Primary Category: Functional ingredient โ antioxidant preservative booster
Secondary Functions: Free radical scavenging,anti-aging
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%โ1%
SOURCING & ETHICS
Vegan Status: Yes โ natural from plants or synthetic
Halal Status: Yes
Source Notes: Plant-derived extract or synthetic.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; well-tolerated.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Hydroxyacetophenone's natural occurrence in fruits (pear, raspberry, passion fruit) at detectable concentrations provides clean-label justification for use in natural cosmetics. its cosmos certification acceptance reflects the growing demand for functional preservation ingredients that meet natural certification criteria โ an ingredient with genuine plant-origin credentials that provides meaningful antimicrobial and antioxidant functions simultaneously.
Last Verified: Cosing database,cosmos-standard approved ingredients,cir safety assessment
Primary Sources: 2026-03-12