NEUTROGENA
Neutrogena Hydro Boost Hyaluronic Acid Night Cream 50G
Neutrogena Hydro Boost Hyaluronic Acid Night Cream 50G
NEUTROGENA
neutrogena-hydro-boost-hyaluronic-acid-night-cream-50g
Moisturize
10084705894693
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Highlights
WHAT IS IT?
Night Cream, 39 ingredients
FEATURES
Effectively recharges hydration overnight, complements skin’s natural night time circadian cycle, improves skin firmness and elasticity, dermatologist tested, rich texture for overnight hydration, reduces dry lines, achieves smoother skin
BEST FOR
dry
CHECKS
Not suitable for children under 3 years old, For external use only, Avoid contact with eyes
Who Is It For?
Adults All GendersWhat Does It Help With?
Hydration Skin Firmness Elasticity Reduces Appearance Of Dry Lines Improves Skin Smoothness Reduces Uneven Skin Tone Fine Lines And WrinklesBudget
Premium ($76-$150)How To Use
Which routine should it be used in?
Instructions:
Key Information
What NEUTROGENA Says
Product Description:
As cells renew at night, Neutrogena Hydro Boost Hyaluronic Acid Night Cream skin health overnight to effectively recharge hydration so that you wake up to an amazingly hydrated, soft and supple skin. Our formulation complements your skin’s natural night time circadian cycle to replenish hydrated skin, reveal visibly healthy glow and reduce the appearance of uneven skin tone, fine lines & wrinkles. Uniquely formulated with Peptide that helps improves skin firmness and elasticity at night for visibly firm, supple, and glowing skin everyday! Dermatologist tested. Rich texture for overnight hydration. 80% showed reduction in appearance of dry lines in 2 weeks. 94% achieved smoother skin in 4 weeks. Based on clinical study conducted at SGS Stephens, Inc., Phoenix Research Center & Dallas Research Center, 41 participants completed study in Dec 2021 to Jan 2022 in USA.
About the Brand:
Ingredients Overview
Ingredients List
Water,Glycerin,Isopropyl-Palmitate,Cetyl-Alcohol,Cetearyl-Olivate,Sorbitan-Olivate,Caprylyl-Glycol,Ethylhexyglycerin,Betaine,Dimethicone,Palmitic-Acid,Stearic-Acid,Polyacrylate-Crosspolymer-6,Pentylene-Glycol,Sodium-PCA,Carnosine,Fructose,Sodium-Hyaluronate,Sodium-Lactate,Urea,Citric-Acid,PCA,1,2-Hexanediol,Sodium-Hydroxide,Fragrance,Maltose,Serine,Alanine,Sodium-Chloride,Trehalose,Glycine,Allantoin,Glutamic-Acid,Lysine-HCL,Threonine,Arginine,Tropolone,Glucose,Proline
Key Ingredients
Hyaluronic Acid, Peptide, Glycerin
Ingredients Details
1-2-hexanediol
Common Name(s): 1-2-hexanediol,cosmetic active,functional ingredient
CAS Number: N/a
DESCRIPTION
What It Does: Delivers characteristic cosmetic function at recommended use concentration.
Why It's Used: Selected for functional contribution and formulation compatibility supported by cosmetic science and regulatory safety data.
How It Works: Works through the mechanism of its molecular class — physicochemical or biological interaction with skin proteins, lipids, or receptors as documented in peer-reviewed cosmetic literature.
Typically Found In: Skin care formulations
TECHNICAL DETAILS
Primary Category: Active ingredient – cosmetic active
Secondary Functions: Skin conditioning
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%–10%
SOURCING & ETHICS
Vegan Status: Conditional
Halal Status: Yes
Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 0/5 – non-comedogenic
Sensitivity Concerns: Well-tolerated by most skin types.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.
Works Well With: Standard skincare actives
Avoid Combining With: No known significant incompatibilities
SCIENTIFIC NOTE
1-2-hexanediol has an established safety and efficacy profile within the cosmetic regulatory framework at standard use concentrations.
Last Verified: Cosing database,1-2-hexanediol technical literature
Primary Sources: 2026-03-12
Alanine
Common Name(s): L-alanine,2-aminopropanoic acid
CAS Number: 56-41-7
DESCRIPTION
What It Does: Provides nmf-type humectant moisture retention and skin conditioning.
Why It's Used: Simple, well-tolerated nmf amino acid humectant for skin conditioning formulations.
How It Works: Small methyl side chain contributes to protein hydrophobic core but as free amino acid provides direct humectant activity via amino and carboxyl groups. converted to pyruvate for cellular atp production via gluconeogenesis.
Typically Found In: Nmf moisturizers,skin conditioning products
TECHNICAL DETAILS
Primary Category: Active ingredient – amino acid
Secondary Functions: Nmf component,cellular energy
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.5%–5%
SOURCING & ETHICS
Vegan Status: Yes – plant-derived or synthetic
Halal Status: Yes
Source Notes: Fermentation-derived or synthetic. natural skin component.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 0/5 – non-comedogenic
Sensitivity Concerns: Non-irritating; endogenous skin molecule.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. natural skin nmf component. ewg score: 1.
Works Well With: Hyaluronic acid,ceramides,peptides,other amino acids
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Free alanine is among the most abundant amino acids in the stratum corneum nmf, where it contributes to the aqueous phase hydration that keeps the stratum corneum flexible and functional.
Last Verified: Cosing database,cir safety assessment
Primary Sources: 2026-03-12
Allantoin
Common Name(s): 5-ureidohydantoin,glyoxyldiureide,aluminum dihydroxy allantoinate
CAS Number: 97-59-6
DESCRIPTION
What It Does: Soothes irritation, accelerates wound healing, promotes skin cell renewal, and provides mild keratolytic exfoliation.
Why It's Used: Gold standard multi-function soothing active – one of the most widely used cosmetic ingredients across all product types for its exceptional tolerability and clinically proven multi-action skin conditioning.
How It Works: Promotes keratinocyte proliferation and fibroblast migration for wound healing. mild keratolytic activity by disrupting corneocyte binding. anti-irritant via direct protein binding and anti-inflammatory cytokine reduction. humectant activity via hydroxyl groups.
Typically Found In: Post-procedure products,sensitive skin formulas,wound care,anti-acne treatments,baby products
TECHNICAL DETAILS
Primary Category: Active ingredient – soothing / anti-inflammatory
Secondary Functions: Wound healing,keratolytic,anti-irritant
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%–2%
SOURCING & ETHICS
Vegan Status: Yes – synthetic or comfrey-derived
Halal Status: Yes
Source Notes: Plant-derived extract or synthetic.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 0/5 – non-comedogenic
Sensitivity Concerns: Exceptionally well-tolerated; suitable for all skin types including baby and compromised skin.
Safe for Sensitive Skin: Yes – particularly recommended for sensitive skin
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Ceramides,panthenol,allantoin,hyaluronic acid,centella asiatica
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Allantoin's keratinocyte proliferation stimulation occurs via receptor-mediated signaling (possibly machr activation) rather than non-specific irritation-driven proliferation, making it a true wound-healing stimulant rather than a pro-inflammatory proliferative signal.
Last Verified: Cosing database,cir safety assessment,araújo et al. allantoin review
Primary Sources: 2026-03-12
Arginine
Common Name(s): L-arginine,2-amino-5-guanidinopentanoic acid
CAS Number: 74-79-3
DESCRIPTION
What It Does: Conditions skin, attracts moisture, supports wound healing, and improves microcirculation via no synthesis.
Why It's Used: Multi-functional amino acid for skin hydration, conditioning, and wound healing in peptide and nmf formulations.
How It Works: Guanidinium group binds water (humectant). substrate for nitric oxide synthase (enos) producing nitric oxide that vasodilates capillaries improving skin nutrition. stimulates fibroblast proliferation for wound healing.
Typically Found In: Anti-aging serums,wound healing products,nmf moisturizers,scalp treatments
TECHNICAL DETAILS
Primary Category: Active ingredient – amino acid
Secondary Functions: Wound healing,microcirculation,nmf component
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.5%–5%
SOURCING & ETHICS
Vegan Status: Yes – plant-derived or synthetic
Halal Status: Yes
Source Notes: Fermentation-derived or synthetic. natural skin component.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 0/5 – non-comedogenic
Sensitivity Concerns: Non-irritating; endogenous skin molecule.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. natural skin nmf component. ewg score: 1.
Works Well With: Hyaluronic acid,ceramides,peptides,other amino acids
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Arginine is a conditionally essential amino acid in wound healing where local demand exceeds synthesis capacity. topical arginine provides the nos substrate locally for no-mediated vasodilation and immune cell function in healing tissue.
Last Verified: Cosing database,cir safety assessment,witte & barbul arginine wound healing review
Primary Sources: 2026-03-12