Paul Mitchell Extra-Body Shampoo

DESCRIPTION

What It Does: Provides antimicrobial skin conditioning with deodorant activity and preservation system enhancement.

Why It's Used: Multifunctional clean beauty preservation active — ethylhexylglycerin provides antimicrobial, deodorant, and skin conditioning in a single ingredient accepted in most natural cosmetic certification schemes.

How It Works: Glycerol ether provides antimicrobial via bacterial membrane phospholipid disruption. deodorant activity via reduction of underarm lipase enzyme activity (similar mechanism to triethyl citrate). skin conditioning from glycerol humectant component. synergistic with phenoxyethanol and diols.

Typically Found In: Natural preservation systems,deodorants,skin conditioning products

TECHNICAL DETAILS

Primary Category: Functional ingredient – antimicrobial glycerol ether

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–0.5%

SOURCING & ETHICS

Vegan Status: Yes – synthetic

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Ethylhexylglycerin's deodorant mechanism is pharmacologically identical to triethyl citrate: both inhibit skin surface microbial lipase enzymes that convert odourless triglycerides to odorous free fatty acids. the glycerol ether structure of ethylhexylglycerin, combined with the 2-ethylhexyl chain, provides lipase inhibition similar to ester-based lipase inhibitors from a different chemical class.

Last Verified: Cosing database,schülke sensiva sc 10 technical data,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Delivers characteristic cosmetic function at recommended use concentration.

Why It's Used: Selected for functional contribution and formulation compatibility supported by cosmetic science and regulatory safety data.

How It Works: Works through the mechanism of its molecular class as documented in peer-reviewed cosmetic literature.

Typically Found In: Skin care formulations

TECHNICAL DETAILS

Primary Category: Active ingredient – cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–10%

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Methylchloroisothiazolinone has an established safety profile within the cosmetic regulatory framework at standard use concentrations.

Last Verified: Cosing database,methylchloroisothiazolinone technical literature

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides highly potent broad-spectrum preservation at very low concentrations in rinse-off formulations.

Why It's Used: Most potent cosmetic preservative — mit provides effective preservation at concentrations 10-100× lower than most other preservatives, enabling clean-label preservation at minimal ingredient load.

How It Works: Electrophilic isothiazolinone ring reacts with bacterial thiol enzymes (glutathione, coa-dependent enzymes) via michael addition for rapid kill. very potent — mic vs e. coli 0.06μg/ml (vs phenoxyethanol mic ~400μg/ml — 6000× more potent). rapidly biodegradable.

Typically Found In: Rinse-off shampoos,body washes,conditioners

TECHNICAL DETAILS

Primary Category: Functional ingredient – isothiazolinone preservative

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.0015%–0.0015% (max 15ppm eu rinse-off)

SOURCING & ETHICS

Vegan Status: Yes – synthetic

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Eu regulation 2014/1298: mit banned from leave-on products. max 15ppm in rinse-off only. contact sensitiser — causes occupational dermatitis epidemic in hairdressers and consumers. sccs noted no safe level for leave-on. 2016 eu restriction driven by major sensitisation epidemic.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Mit's sensitisation epidemic (2010-2015) is one of the most significant cosmetic safety events in modern dermatology: a dramatic increase in contact allergy patch test positive rates from <1% (2005) to 7% (2015) in the eu was directly traceable to the widespread introduction of mit in leave-on products. this epidemic prompted the fastest eu cosmetic regulatory action in history and demonstrates the critical importance of patch test surveillance in monitoring emerging cosmetic allergens.

Last Verified: Cosing database,eu regulation 2014/1298,yazar et al. mit sensitisation epidemic study

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Panthenol deeply moisturizes skin and hair, soothes irritation, accelerates wound healing, strengthens the skin barrier, and improves hair elasticity and shine.

Why It's Used: It is used because it is exceptionally versatile, working in both skin and hair formulations. it is gentle enough for sensitive and post-procedure skin, and converts to the active vitamin b5 within the skin.

How It Works: Panthenol penetrates skin and hair, where it is oxidized to pantothenic acid (vitamin b5), a coenzyme a precursor essential to metabolism. in skin, it acts as a humectant and stimulates fibroblast proliferation. in hair, it coats the shaft, improving manageability.

Typically Found In: Moisturizers,serums,toners,after-sun products,wound healing products,shampoos,conditioners,hair masks,beard care

TECHNICAL DETAILS

Primary Category: Active ingredient – provitamin b5

Secondary Functions: Anti-inflammatory,wound healing,hair conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.5%–5% (typical: 1–3%)

SOURCING & ETHICS

Vegan Status: Yes – synthetically produced

Halal Status: Yes

Source Notes: Commercially synthesized. both d- and dl-forms used in cosmetics; d-panthenol is the biologically active isomer but dl-panthenol is less expensive and widely used.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low; one of the most soothing ingredients in cosmetics

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Extremely rare contact allergy; considered one of the safest cosmetic ingredients. suitable for all skin types.

Safe for Sensitive Skin: Yes – ideal for sensitive, reactive, and post-procedure skin

SAFETY & COMPATIBILITY

Safety Profile: Exceptionally safe. ewg hazard score: 1. no significant concerns for irritation, sensitization, or systemic toxicity. safe during pregnancy.

Works Well With: Hyaluronic acid,ceramides,allantoin,niacinamide,centella asiatica,retinol (reduces irritation),glycerin

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Panthenol has demonstrated wound-healing properties in clinical studies, stimulating fibroblast proliferation and migration. its dual humectant and anti-inflammatory action makes it particularly effective in barrier-repair formulations.

Last Verified: Cosing database,cir safety assessment,ebner et al. (2002) skin pharmacology and applied skin physiology

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Panthenol deeply moisturizes skin and hair, soothes irritation, accelerates wound healing, strengthens the skin barrier, and improves hair elasticity and shine.

Why It's Used: It is used because it is exceptionally versatile, working in both skin and hair formulations. it is gentle enough for sensitive and post-procedure skin, and converts to the active vitamin b5 within the skin.

How It Works: Panthenol penetrates skin and hair, where it is oxidized to pantothenic acid (vitamin b5), a coenzyme a precursor essential to metabolism. in skin, it acts as a humectant and stimulates fibroblast proliferation. in hair, it coats the shaft, improving manageability.

Typically Found In: Moisturizers,serums,toners,after-sun products,wound healing products,shampoos,conditioners,hair masks,beard care

TECHNICAL DETAILS

Primary Category: Active ingredient – provitamin b5

Secondary Functions: Anti-inflammatory,wound healing,hair conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.5%–5% (typical: 1–3%)

SOURCING & ETHICS

Vegan Status: Yes – synthetically produced

Halal Status: Yes

Source Notes: Commercially synthesized. both d- and dl-forms used in cosmetics; d-panthenol is the biologically active isomer but dl-panthenol is less expensive and widely used.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low; one of the most soothing ingredients in cosmetics

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Extremely rare contact allergy; considered one of the safest cosmetic ingredients. suitable for all skin types.

Safe for Sensitive Skin: Yes – ideal for sensitive, reactive, and post-procedure skin

SAFETY & COMPATIBILITY

Safety Profile: Exceptionally safe. ewg hazard score: 1. no significant concerns for irritation, sensitization, or systemic toxicity. safe during pregnancy.

Works Well With: Hyaluronic acid,ceramides,allantoin,niacinamide,centella asiatica,retinol (reduces irritation),glycerin

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Panthenol has demonstrated wound-healing properties in clinical studies, stimulating fibroblast proliferation and migration. its dual humectant and anti-inflammatory action makes it particularly effective in barrier-repair formulations.

Last Verified: Cosing database,cir safety assessment,ebner et al. (2002) skin pharmacology and applied skin physiology

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Prevents microbial contamination and spoilage in cosmetic formulations.

Why It's Used: The benchmark cosmetic preservative – eu-permitted up to 1%, effective against virtually all cosmetically relevant microorganisms, and excellent tolerability.

How It Works: Phenol ring provides broad antimicrobial activity via disruption of bacterial and fungal cell membranes and inhibition of enzymatic activity. effective against gram-positive and gram-negative bacteria, yeasts (candida), and molds (aspergillus). activity ph range: 3-9.

Typically Found In: All cosmetic formulations as primary preservative

TECHNICAL DETAILS

Primary Category: Functional ingredient – broad-spectrum preservative

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–1% (eu max 1%)

SOURCING & ETHICS

Vegan Status: Yes – synthetic

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Eu cosmetics regulation max 1%. sccs assessed as safe at ≤1%. avoid use around eyes in baby products per some country regulations. ewg score: 4.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Phenoxyethanol's widespread adoption as the primary cosmetic preservative followed the phaseout of parabens from many formulations in the 2000s-2010s. despite having a comparable or better safety profile to parabens, it is often cited in 'free-from' formulations – a consumer perception issue rather than a scientific safety concern.

Last Verified: Cosing database,sccs opinion on phenoxyethanol,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides documented cosmetic activity from polyquaternium-44.

Why It's Used: Polyquaternium-44 delivers formulation value through its specific biological activity and established safety and efficacy.

How It Works: Source: polyquaternium-44. mechanism: documented in cosmetic literature. safety: cosing-reviewed. standard cosmetic use concentrations.

Typically Found In: Skin care formulations,active products

TECHNICAL DETAILS

Primary Category: Active ingredient – antioxidant

Secondary Functions: Free radical scavenging,anti-aging

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–5%

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Yes

Source Notes: Plant-derived extract or synthetic.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; well-tolerated.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Polyquaternium-44 provides cosmetic activity through its characteristic mechanism. at standard concentrations it delivers documented biological activity with an established safety profile from cosmetic science literature and regulatory review.

Last Verified: Cosing database,polyquaternium-44 technical literature

Primary Sources: 2026-03-12