
Highlights
WHAT IS IT?
Moisturizing cream with physiological lipids
FEATURES
Hypoallergenic, moisturizes dry and sensitive skin, contains no colourants, perfume or preservatives, contains Derma Membrane Structure (DMS)
BEST FOR
sensitive
CHECKS
No colourants, no perfume, no preservatives
Who Is It For?
All Genders No Specific Age Range ProvidedWhat Does It Help With?
Dry Skin Sensitive Skin Conditions Moisture Barrier RepairBudget
Premium ($76-$150)How To Use
Which routine should it be used in?
Instructions:
Key Information
What PHYSIOGEL Says
Product Description:
Physiogel Cream is a hypoallergenic, moisturizing cream that provides physiological lipids in Derma Membrane Structure (DMS), a structure similar to the skin, hence revitalizing dry skin. Physiological lipids are natural and essential components of normal healthy skin. The unique formula of Physiogel Cream contains no colourants, perfume and preservatives to enhance its hypoallergenic effect. For the daily care of dry and sensitive skin conditions.
About the Brand:
Ingredients Overview
Ingredients List
Water,Caprylic/Capric-Triglyceride,Glycerin,Pentylene-Glycol,Cocos-Nucifera,Hydrogenated-Lecithin,Butyrospermum-Parkii,Hydroxyethylcellulose,Squalane,Sodium-Carbomer,Xanthan-Gum,Carbomer,Ceramide-3
Key Ingredients
Ceramide-3, Squalane, Glycerin, Butyrospermum Parkii
Ingredients Details
Carbomer
Common Name(s): Carbopol,polyacrylic acid,carboxyvinyl polymer
DESCRIPTION
What It Does: Provides transparent gel textures and thickening at very low concentrations via ph-responsive swelling.
Why It's Used: The most widely used gel thickener โ provides crystal-clear, stable gels at concentrations as low as 0.1-0.5% with ph-controlled viscosity.
How It Works: Highly crosslinked polyacrylic acid remains tightly coiled at acidic ph. neutralization with naoh or triethanolamine ionizes carboxylic groups causing electrostatic repulsion that unfolds and swells the polymer coils, dramatically increasing viscosity. concentration-dependent thickening.
Typically Found In: Gels,serums,emulsions,sunscreens
TECHNICAL DETAILS
Primary Category: Functional ingredient โ polyacrylic acid thickener
Secondary Functions: Skin conditioning
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%โ2%
SOURCING & ETHICS
Vegan Status: Yes โ synthetic
Halal Status: Yes
Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Well-tolerated by most skin types.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Good safety profile at recommended concentrations. ewg score: 1โ2.
Works Well With: Standard skincare actives
Avoid Combining With: No known significant incompatibilities
SCIENTIFIC NOTE
Carbomer's ph-responsive swelling mechanism provides an elegant formulation control tool: a neutralized gel can be liquefied by ph reduction (adding acid) and re-thickened by reneutralization. this reversible rheology control allows two-phase products that mix on application without the need for mechanical emulsification.
Last Verified: Cosing database,cir safety assessment
Primary Sources: 2026-03-12
Glycerin
Common Name(s): Glycerol,glycerine,1,2,3-propanetriol
CAS Number: 56-81-5
DESCRIPTION
What It Does: Glycerin pulls water from the environment and deeper skin layers into the outer skin layer (epidermis), boosting moisture levels and keeping skin soft, smooth, and plump.
Why It's Used: It is used in virtually every moisturizer, serum, and cleanser because it is highly effective at hydrating skin, is well-tolerated by all skin types, and enhances the texture and spreadability of formulations.
How It Works: As a humectant, glycerin forms hydrogen bonds with water molecules, trapping them in the skin. it also reinforces the skin barrier by integrating into lipid structures between skin cells.
Typically Found In: Moisturizers,serums,cleansers,toners,sheet masks,sunscreens,body lotions,shampoos,conditioners
TECHNICAL DETAILS
Primary Category: Humectant
Secondary Functions: Skin barrier support,emollient,solvent
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 1%โ30% (typical: 3โ10%)
SOURCING & ETHICS
Vegan Status: Yes โ plant-derived (coconut, soy, palm) or synthetic
Halal Status: Yes โ when plant-derived or synthetic; verify source with supplier
Source Notes: Derived from plant oils via hydrolysis or saponification; synthetic versions also available. palm-derived glycerin carries sustainability concerns.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low; non-irritating at all standard concentrations
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Extremely rare allergic reactions; generally safe for all skin types including sensitive and baby skin
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Widely recognized as safe. ewg hazard score: 1. no significant concerns for irritation, sensitization, or toxicity at typical concentrations (up to 50%).
Works Well With: Hyaluronic acid,ceramides,niacinamide,panthenol,urea,peptides,retinol,ahas/bhas
Avoid Combining With: No known incompatibilities at standard concentrations
SCIENTIFIC NOTE
Glycerin is an endogenous skin component found naturally in the stratum corneum. aquaporin-3 channels in keratinocytes facilitate glycerin transport, making it integral to natural skin hydration pathways.
Last Verified: Cosing database,cir safety assessment,ewg skin deep,inci decoder
Primary Sources: 2026-03-12
Hydroxyethylcellulose
Common Name(s): Hec,natrosol,ethylhydroxyethylcellulose
CAS Number: 9004-62-0
DESCRIPTION
What It Does: Provides non-ionic thickening compatible with anionic surfactants and electrolyte-containing formulations.
Why It's Used: Non-ionic cellulose thickener for surfactant systems where anionic/cationic thickener incompatibility is a concern.
How It Works: Hydroxyethyl substitution disrupts cellulose crystallinity enabling water solubility. non-ionic nature provides compatibility with anionic, cationic, and amphoteric surfactants. pseudoplastic rheology provides shear-thinning for dispensing. film formation from cellulose backbone.
Typically Found In: Shampoos,body washes,clear gels,surfactant systems
TECHNICAL DETAILS
Primary Category: Functional ingredient โ cellulose thickener
Secondary Functions: Tewl reduction,skin plumping
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%โ3%
SOURCING & ETHICS
Vegan Status: Yes โ from cellulose (plant)
Halal Status: Yes
Source Notes: Synthetic or naturally derived. excellent aqueous solubility.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; suitable for all skin types.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Ceramides,emollients,occlusives,glycerin,hyaluronic acid
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Hydroxyethylcellulose's non-ionic character is its primary differentiator from anionic carboxymethylcellulose โ the absence of ionizable groups means hec maintains stable viscosity across ph 2-12 and at high electrolyte concentrations where carboxymethylcellulose destabilizes. this ionic independence makes hec the preferred cellulose thickener for acidic and salt-containing formulations.
Last Verified: Cosing database,ashland hec technical data,cir safety assessment
Primary Sources: 2026-03-12
Squalane
Common Name(s): Perhydrosqualene,2,6,10,15,19,23-hexamethyltetracosane
CAS Number: 0111-01-03
DESCRIPTION
What It Does: Provides endogenous-skin-identical emolliency with exceptional stability and skin compatibility.
Why It's Used: The most skin-compatible emollient โ chemically identical to human sebum squalene component with outstanding tolerability across all skin types.
How It Works: Fully saturated hydrocarbon with zero oxidation sites provides exceptional stability unlike squalene's 6 double bonds. integrates into stratum corneum lipid bilayers with near-perfect biocompatibility. provides antioxidant protection to formulation via radical quenching.
Typically Found In: Facial oils,serums,non-comedogenic moisturizers,luxury body care
TECHNICAL DETAILS
Primary Category: Functional ingredient โ emollient
Secondary Functions: Maximum biocompatibility,antioxidant stabilizer,non-comedogenic
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 1%โ100%
SOURCING & ETHICS
Vegan Status: Conditional โ plant-derived (sugarcane, olive) preferred; shark liver-derived being phased out
Halal Status: Yes โ plant-derived
Source Notes: Sustainable plant-derived squalane from sugarcane fermentation (amyris) or olive oil fractionation is preferred over shark liver-derived. chemically identical regardless of source.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Humectants,ceramides,actives as carrier
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Squalene constitutes approximately 12-15% of human sebum โ the highest proportion of any skin lipid. topical squalane (stable, hydrogenated form) replenishes this abundant endogenous skin lipid. the complete absence of oxidizable double bonds (unlike squalene's 6 double bonds) eliminates the pro-oxidant concerns of natural squalene oxidation.
Last Verified: Cosing database,huang et al. squalane review,cir safety assessment
Primary Sources: 2026-03-12