Pureology Hydrate Conditioner for Dry Hair

DESCRIPTION

What It Does: Provides amino group-mediated preferential adsorption to damaged hair for targeted conditioning.

Why It's Used: Premium hair conditioning silicone – amino groups provide substantive adsorption to hair far exceeding pdms, with automatic targeting to the most damaged areas requiring conditioning.

How It Works: Amino (nh2) groups on silicone chain provide cationic character at normal ph, electrostatic adsorption to anionic hair surface. higher charge density at damaged sites increases adsorption where conditioning is most needed. si-o-si backbone provides permanent conditioning film with heat protection.

Typically Found In: Intensive conditioners,anti-frizz products,damage repair conditioners

TECHNICAL DETAILS

Primary Category: Functional ingredient – amino-functional silicone

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–5%

SOURCING & ETHICS

Vegan Status: Yes – synthetic

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Amodimethicone's amino group-driven substantivity to damaged hair is dramatically greater than non-functionalized pdms. studies show amodimethicone deposits 50-200× more mass on bleach-damaged hair vs virgin hair, providing an automatic 'damage detection' conditioning system that directs the most conditioning to the hair areas that need it most.

Last Verified: Cosing database,robbins hair science,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Absorbs or reflects uv radiation, preventing uv-induced dna damage, photo-oxidative stress, and premature skin aging.

Why It's Used: Uv filters are the active ingredients in sun protection — without them, formulations cannot make spf claims or prevent solar-induced skin damage.

How It Works: The uv-absorbing chromophore undergoes photoexcitation by uv photons, then dissipates the absorbed energy through thermal relaxation (chemical filters) or photon scattering/reflection (physical filters), preventing photon penetration to skin cells.

Typically Found In: Sunscreens,moisturizers with spf,foundations with spf

TECHNICAL DETAILS

Primary Category: Uv filters

Secondary Functions: Skin-protecting

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.5–25% (within regulatory limits)

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Synthetic uv filter; no animal components.

SKIN COMPATIBILITY

Irritancy Rating: 1

Comedogenicity Rating: 0

Sensitivity Concerns: Contact allergy to uv filters occurs in approximately 1–3% of the general population; patch testing recommended for those with known photosensitivity.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Regulatory approval required per market (eu annex vi, fda otc monograph, etc.). generally non-irritating at approved concentrations.

Works Well With: Other uv filters,antioxidants,emollients

Avoid Combining With: Incompatible filter combinations (photodegradation); check regulatory approvals per region

SCIENTIFIC NOTE

Uv filters operate through two mechanisms: organic/chemical filters absorb uv photons through electronic excitation (π→π* transitions in conjugated systems), then dissipate energy via thermal relaxation; inorganic/physical filters (tio2, zno) scatter and reflect photons through mie scattering (particle size 50–300 nm) and band gap absorption. spf is measured in vivo (iso 24444) as the ratio of minimal erythema doses with and without sunscreen.

Last Verified: Cosing eu database; pcpc cosmetic ingredient safety reviews; eu cosmetics regulation annex vi; iso 24444 (in vivo spf testing)

Primary Sources: 2025-01-15

DESCRIPTION

What It Does: Provides the defining fresh citrus fragrance note alongside solvent and antimicrobial properties.

Why It's Used: The citrus industry's primary fragrance compound and the most abundant terpene in essential oils – limonene provides the clean, universally appealing fresh citrus scent character.

How It Works: D-limonene activates trpv1 mildly at high concentrations. antimicrobial via membrane disruption. solvent for oils and lipophilic compounds. cleaning via emulsification of lipid soils.

Typically Found In: Citrus-scented products,cleaning products,fragrance compounds

TECHNICAL DETAILS

Primary Category: Fragrance component – cyclic monoterpene

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.001%–3%

SOURCING & ETHICS

Vegan Status: Yes – from citrus peel essential oils

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Eu cosmetics regulation: declared fragrance allergen. oxidises to sensitising compounds (limonene hydroperoxides) on air exposure – use with antioxidant stabilisers. ifra guidelines apply.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Limonene's sensitisation risk arises not from limonene itself but from its autooxidation products (limonene-1,2-epoxide and limonene hydroperoxides) formed on air exposure. fresh limonene has low sensitisation potential, but air-oxidised limonene's hydroperoxide products are potent skin sensitisers. this explains why oxidation-stabilised formulations (with bht or other antioxidants) are required to manage limonene safety.

Last Verified: Cosing database,ifra standards,bråred christensson et al. limonene oxidation study

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides the most common natural floral-citrus fragrance note with additional anti-inflammatory properties.

Why It's Used: The most abundant fragrance terpene in nature – linalool forms the primary scent character of lavender, responsible for lavender's documented aromatherapy calming effects.

How It Works: Monoterpene alcohol activates gaba-a receptors for anti-anxiety activity (same receptor as benzodiazepines). inhibits glutamate-induced excitotoxicity. antimicrobial via membrane disruption. anti-inflammatory via nf-kb inhibition.

Typically Found In: Virtually all fragranced cosmetics

TECHNICAL DETAILS

Primary Category: Fragrance component – tertiary terpene alcohol

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.001%–3%

SOURCING & ETHICS

Vegan Status: Yes – from lavender, coriander, bergamot

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Eu cosmetics regulation: declared fragrance allergen on label when >0.001% (leave-on) or >0.01% (rinse-off). ifra guidelines apply.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Linalool's gaba-a receptor activation provides a pharmacological basis for lavender aromatherapy's documented anxiolytic effects. the same receptor modulation used by benzodiazepine drugs (such as diazepam) is activated by inhaled linalool vapor, providing receptor-mediated calming without the tolerance and dependence associated with pharmaceutical gaba-a modulators.

Last Verified: Cosing database,ifra standards,elisabetsky et al. linalool gaba study

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Activates trpm8 cold thermoreceptors for intense cooling sensation and analgesic activity.

Why It's Used: The most potent cosmetic cooling agent – direct trpm8 agonist providing cooling sensation without actual temperature reduction for refreshing and analgesic formulations.

How It Works: Potent trpm8 (menthol receptor/cold thermosensor) agonist – activation at room temperature mimics cold sensation without actual cooling. anti-pruritic via trpm8 activation competing with itch c-fiber signaling. antimicrobial via membrane disruption.

Typically Found In: Cooling products,scalp treatments,oral care,pain relief,foot care,after-sun

TECHNICAL DETAILS

Primary Category: Active ingredient – cooling sensory terpenoid

Secondary Functions: Redness reduction,anti-inflammatory,calming

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–2%

SOURCING & ETHICS

Vegan Status: Yes – from mentha piperita or synthetic

Halal Status: Yes

Source Notes: Plant-derived extract or synthetic.

SKIN COMPATIBILITY

Irritancy Rating: 2/5 – low to moderate; potential sensitizer

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; ideal for reactive and sensitive skin.

Safe for Sensitive Skin: Avoid near eyes. use with caution at concentrations above 1% for sensitive skin.

SAFETY & COMPATIBILITY

Safety Profile: Eu max 4.5% (leave-on); regulations vary by application site. avoid on infants' face.

Works Well With: Ceramides,panthenol,allantoin,hyaluronic acid,centella asiatica

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Menthol's exceptional cooling potency stems from its ec50 for trpm8 activation of approximately 10μm (vs camphor's ec50 of ~5mm – 500× lower potency). this 500× potency advantage explains why even tiny concentrations of menthol provide intense cooling, while much higher concentrations of camphor are required for equivalent sensation.

Last Verified: Cosing database,mckemy et al. menthol trpm8 discovery,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Panthenol deeply moisturizes skin and hair, soothes irritation, accelerates wound healing, strengthens the skin barrier, and improves hair elasticity and shine.

Why It's Used: It is used because it is exceptionally versatile, working in both skin and hair formulations. it is gentle enough for sensitive and post-procedure skin, and converts to the active vitamin b5 within the skin.

How It Works: Panthenol penetrates skin and hair, where it is oxidized to pantothenic acid (vitamin b5), a coenzyme a precursor essential to metabolism. in skin, it acts as a humectant and stimulates fibroblast proliferation. in hair, it coats the shaft, improving manageability.

Typically Found In: Moisturizers,serums,toners,after-sun products,wound healing products,shampoos,conditioners,hair masks,beard care

TECHNICAL DETAILS

Primary Category: Active ingredient – provitamin b5

Secondary Functions: Anti-inflammatory,wound healing,hair conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.5%–5% (typical: 1–3%)

SOURCING & ETHICS

Vegan Status: Yes – synthetically produced

Halal Status: Yes

Source Notes: Commercially synthesized. both d- and dl-forms used in cosmetics; d-panthenol is the biologically active isomer but dl-panthenol is less expensive and widely used.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low; one of the most soothing ingredients in cosmetics

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Extremely rare contact allergy; considered one of the safest cosmetic ingredients. suitable for all skin types.

Safe for Sensitive Skin: Yes – ideal for sensitive, reactive, and post-procedure skin

SAFETY & COMPATIBILITY

Safety Profile: Exceptionally safe. ewg hazard score: 1. no significant concerns for irritation, sensitization, or systemic toxicity. safe during pregnancy.

Works Well With: Hyaluronic acid,ceramides,allantoin,niacinamide,centella asiatica,retinol (reduces irritation),glycerin

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Panthenol has demonstrated wound-healing properties in clinical studies, stimulating fibroblast proliferation and migration. its dual humectant and anti-inflammatory action makes it particularly effective in barrier-repair formulations.

Last Verified: Cosing database,cir safety assessment,ebner et al. (2002) skin pharmacology and applied skin physiology

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Prevents microbial contamination and spoilage in cosmetic formulations.

Why It's Used: The benchmark cosmetic preservative – eu-permitted up to 1%, effective against virtually all cosmetically relevant microorganisms, and excellent tolerability.

How It Works: Phenol ring provides broad antimicrobial activity via disruption of bacterial and fungal cell membranes and inhibition of enzymatic activity. effective against gram-positive and gram-negative bacteria, yeasts (candida), and molds (aspergillus). activity ph range: 3-9.

Typically Found In: All cosmetic formulations as primary preservative

TECHNICAL DETAILS

Primary Category: Functional ingredient – broad-spectrum preservative

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–1% (eu max 1%)

SOURCING & ETHICS

Vegan Status: Yes – synthetic

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Eu cosmetics regulation max 1%. sccs assessed as safe at ≤1%. avoid use around eyes in baby products per some country regulations. ewg score: 4.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Phenoxyethanol's widespread adoption as the primary cosmetic preservative followed the phaseout of parabens from many formulations in the 2000s-2010s. despite having a comparable or better safety profile to parabens, it is often cited in 'free-from' formulations – a consumer perception issue rather than a scientific safety concern.

Last Verified: Cosing database,sccs opinion on phenoxyethanol,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Tocopherol neutralizes free radicals that damage skin cells, protects cell membranes from lipid peroxidation, moisturizes, and helps maintain a healthy skin barrier.

Why It's Used: It is used as both a skin-active antioxidant and a formulation stabilizer (preventing oxidation of other ingredients). it has decades of safety and efficacy evidence and works synergistically with vitamin c.

How It Works: As a chain-breaking antioxidant, tocopherol donates hydrogen atoms to interrupt lipid peroxidation chain reactions. it is regenerated by vitamin c (ascorbic acid) in the vitamins c+e antioxidant cycle, creating a more durable antioxidant defense.

Typically Found In: Moisturizers,serums,oils,sunscreens,eye creams,lip balms,antioxidant formulations,haircare products

TECHNICAL DETAILS

Primary Category: Active ingredient – antioxidant/vitamin e

Secondary Functions: Emollient,formulation stabilizer,barrier support

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–1% (typical: 0.1–0.5% as active; higher as formulation antioxidant)

SOURCING & ETHICS

Vegan Status: Yes – plant-derived (soybean, sunflower, wheat germ oil) or synthetic

Halal Status: Yes – plant-derived or synthetic

Source Notes: Natural d-alpha-tocopherol is derived from plant oils and is more bioactive. synthetic dl-alpha-tocopherol is less expensive. tocopherol acetate (tocopheryl acetate) is the more stable ester form.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low; rare contact sensitivity reported

Comedogenicity Rating: 2/5 – mildly comedogenic at higher concentrations; formulation-dependent

Sensitivity Concerns: A small percentage of people report contact sensitization to tocopherol, particularly with leave-on products. comedogenicity risk is higher in oil-heavy formulations.

Safe for Sensitive Skin: Generally yes; perform patch test if history of vitamin e sensitivity

SAFETY & COMPATIBILITY

Safety Profile: Very safe; widely used. ewg hazard score: 2–3 (depending on concentration). no significant systemic concerns from topical use.

Works Well With: Ascorbic acid (vitamin c) – synergistic antioxidant pair,ferulic acid – stabilizes and boosts both c and e,ceramides,spf,retinol

Avoid Combining With: Very high concentrations of benzoyl peroxide may oxidize tocopherol; potential comedogenicity concerns in acne-prone skin when in heavy oil bases

SCIENTIFIC NOTE

The combination of vitamin c, vitamin e, and ferulic acid (the 'ce ferulic' formulation) provides fourfold photoprotection against uv-induced free radical damage – a synergy documented in landmark research by pinnell et al.

Last Verified: Cosing database,cir safety assessment,pinnell et al. (2005) journal of investigative dermatology,efsa panel on food additives

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Delivers characteristic cosmetic function at recommended use concentration.

Why It's Used: Selected for functional contribution and formulation compatibility supported by cosmetic science and regulatory safety data.

How It Works: Works through the mechanism of its molecular class — physicochemical or biological interaction with skin proteins, lipids, or receptors as documented in peer-reviewed cosmetic literature.

Typically Found In: Skin care formulations

TECHNICAL DETAILS

Primary Category: Active ingredient – cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–10%

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Trideceth-6 has an established safety and efficacy profile within the cosmetic regulatory framework at standard use concentrations.

Last Verified: Cosing database,trideceth-6 technical literature

Primary Sources: 2026-03-12