PREQUEL
REACTIVE SKIN SOLUTIONS
REACTIVE SKIN SOLUTIONS
PREQUEL
reactive-skin-solutions
Moisturize
9873693507877
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Highlights
WHAT IS IT?
Moisturizing cream with 5% ectoin
FEATURES
Steroid-free, soothing solution, renews skin surface, restores skin barrier
BEST FOR
sensitive
CHECKS
Steroid-free
Who Is It For?
All Ages With Sensitive SkinWhat Does It Help With?
Sensitivity Scaling Roughness Redness IrritationBudget
Affordable (under $30)How To Use
Which routine should it be used in?
Instructions:
Key Information
What PREQUEL Says
Product Description:
A steroid-free, soothing solution that renews the skin's surface while restoring compromised skin barrier. Formulated with a potent blend of 5% ectoin, urea, hydroxyethyl urea and allantoin, Prequel's 5% Ectoin Cream alleviates sensitivity, scaling, roughness, redness and irritation while moisturizing the skin.
About the Brand:
Ingredients Overview
Ingredients List
ectoin-5%, urea, hydroxyethyl-urea, allantoin
Key Ingredients
ectoin, urea, hydroxyethyl urea, allantoin
Ingredients Details
Ectoin
Common Name(s): Ectoin,extremophile stress protector,anti-aging humectant
CAS Number: N/a
DESCRIPTION
What It Does: Hydrates by forming a water-shell around skin biomolecules, stabilises cellular membranes against heat/uv stress, and reduces inflammatory cytokine release in stressed skin.
Why It's Used: Provides dual humectancy plus cellular protection โ unique among humectants for its documented ability to stabilise skin proteins and membranes against uv and environmental stress, not just attract water.
How It Works: Ectoin's tetrahydropyrimidine ring forms an ordered hydration shell around proteins, lipid bilayers, and dna through kosmotropic water structuring. this preferential hydration excludes denaturants and uv-stress mediators from biomolecule surfaces while simultaneously providing humectant moisture binding.
Typically Found In: Sensitive skin,uv protection actives,anti-inflammatory
TECHNICAL DETAILS
Primary Category: Functional ingredient โ humectant
Secondary Functions: Tewl reduction,skin plumping
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%โ2%
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Synthetic or naturally derived. excellent aqueous solubility.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; suitable for all skin types.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Ceramides,emollients,occlusives,glycerin,hyaluronic acid
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Extremophile bacteria accumulate ectoin at up to 15% intracellular concentration to survive 100ยฐc temperatures and extreme salinity โ the same biomolecule protection mechanism applies to human skin cells at cosmetic concentrations.
Last Verified: Cosing database,ectoin extremophile anti-stress clinical review
Primary Sources: 2026-03-12