
Highlights
WHAT IS IT?
A skin regeneration cream with advanced growth factors, peptides, and antioxidants
FEATURES
Patented formulation, reduces appearance of fine lines, improves texture and overall skin tone
BEST FOR
Dry, Normal/Combo, Oily skin types
CHECKS
Paraben-free
Who Is It For?
Adults Both Women And MenWhat Does It Help With?
Fine Lines Wrinkles Texture Pore Size Elasticity Skin Clarity/uniformity HydrationBudget
PremiumHow To Use
Which routine should it be used in?
Instructions:
Key Information
What Jan Marini Says
Product Description:
This patented skin regeneration cream combines advanced growth factors, peptides and antioxidants to hydrate skin, reduce the appearance of fine lines and improve the appearance of texture and overall skin tone.
About the Brand:
Ingredients Overview
Ingredients List
Water/Aqua/Eau, Glycerin, Helianthus Annuus (Sunflower) Seed Oil, PEG-40 Hydrogenated Castor Oil, Cyclopentasiloxane, Butylene Glycol, Cetearyl Alcohol, Limnanthes Alba (Meadowfoam) Seed Oil, Mangifera Indica (Mango) Seed Butter, Dimethicone, Glyceryl Stearate, Ceteareth-20, Butyrospermum Parkii (Shea) Butter, Methylsilanol Mannuronate, Cycloastragenol, Ceramide NG, Myristoyl Tetrapeptide-12, Myristoyl Pentapeptide-11, Palmitoyl Pentapeptide-4, Myristoyl Pentapeptide -8, sh-Polypeptide-3, sh-Polypeptide-22, sh-Oligopeptide-1, Panthenol, Sodium Hyaluronate, Linoleic Acid, Linolenic Acid, Camellia Sinensis (Green Tea) Leaf Extract, Allantoin, Ubiquinone, Tocopheryl Acetate, Tocopherol, Magnesium Aluminum Silicate, Dimethicone/Vinyl Dimethicone Crosspolymer , Xanthan Gum, Glycine Soja (Soybean) Oil, Hydrogenated Lecithin, Carbomer, Polysorbate 20, Polysaccharides, Sodium Lactate, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Citric Acid, Quartz, Sodium Oleate, Disodium EDTA, Sorbic Acid, Phenoxyethanol
Key Ingredients
Cycloastragenol, Transforming Growth Factor beta 1, Keratinocyte Growth Factor, Epidermal Growth Factor, Anti-Aging Peptides, Green Tea Extract, CoEnzyme Q10, Hyaluronic Acid, Essential Fatty Acids
Ingredients Details
Butylene Glycol
Common Name(s): 1,3-butanediol,bg,1,3-butylene glycol
CAS Number: 107-88-0
DESCRIPTION
What It Does: Provides humectant hydration and active ingredient solubilization with excellent skin feel.
Why It's Used: Preferred glycol humectant in premium and k-beauty formulations for superior skin feel vs propylene glycol with equivalent functionality.
How It Works: Two hydroxyl groups at 1,3-positions provide water binding and solvent activity. better tolerated than propylene glycol with minimal sensitization risk. 4-carbon backbone provides slightly greater hydrophobic character enabling dissolution of less polar actives vs pg.
Typically Found In: Toners,essences,serums,k-beauty formulas
TECHNICAL DETAILS
Primary Category: Functional ingredient โ glycol humectant
Secondary Functions: Tewl reduction,skin plumping
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 1%โ10%
SOURCING & ETHICS
Vegan Status: Yes โ synthetic
Halal Status: Yes
Source Notes: Synthetic or naturally derived. excellent aqueous solubility.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; suitable for all skin types.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Ceramides,emollients,occlusives,glycerin,hyaluronic acid
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
K-beauty's preference for butylene glycol over propylene glycol is driven by two factors: bg's superior skin feel (less tacky than pg's higher viscosity) and its lower sensitization potential (1,3-bg has better spatial distribution of hydroxyl groups that reduces protein interaction vs pg's 1,2-position oh groups).
Last Verified: Cosing database,cir safety assessment
Primary Sources: 2026-03-12
Cetearyl Alcohol
Common Name(s): Cetostearyl alcohol,c16-18 fatty alcohol
CAS Number: 8005-44-5
DESCRIPTION
What It Does: Provides fatty alcohol emulsification and thickening for stable, well-textured emulsions.
Why It's Used: The most widely used fatty alcohol in cosmetics โ provides emulsification, thickening, and emolliency simultaneously from a single ingredient with excellent safety profile.
How It Works: Forms bilayer lamellar structures in water with emulsifiers creating a viscous structured network that thickens and stabilizes emulsions. fatty alcohol emolliency provides direct skin conditioning. bilayer formation reduces inter-droplet coalescence in emulsions.
Typically Found In: Creams,lotions,conditioners โ virtually all emulsion products
TECHNICAL DETAILS
Primary Category: Functional ingredient โ fatty alcohol emulsifier/thickener
Secondary Functions: Barrier sealing,softening
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 1%โ25%
SOURCING & ETHICS
Vegan Status: Yes โ from vegetable or coconut/palm fatty acids
Halal Status: Yes
Source Notes: Plant-derived, synthetic or animal-derived. verify source.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 1/5 โ low; formulation-dependent
Sensitivity Concerns: Non-irritating.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Humectants,ceramides,actives as carrier
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Cetearyl alcohol's ability to form lamellar liquid crystal structures ('krafft phases') with water and co-emulsifiers provides not only emulsion stability but also enhanced skin penetration via the lamellar skin barrier pathway. these crystalline structures can act as a reservoir for active ingredients, slowly releasing them as the lamellar structure melts on skin contact.
Last Verified: Cosing database,cir safety assessment
Primary Sources: 2026-03-12
Cyclopentasiloxane
Common Name(s): Cyclopentasiloxane,cyclic volatile silicone,dry-touch carrier solvent
CAS Number: N/a
DESCRIPTION
What It Does: Provides a dry, weightless application vehicle that evaporates cleanly leaving actives and non-volatile silicones deposited on skin โ eliminating the residual heaviness of conventional liquid carrier solvents.
Why It's Used: Cyclosiloxanes are the unique volatile silicone solvents that dissolve non-volatile silicones (dimethicone, cyclomethicone), organic uv filters, and lipophilic actives, providing the sensory-superior dry-touch application experience in premium formulations.
How It Works: Cyclosiloxane vapour pressure (d5 cyclopentasiloxane ~0.3 mmhg at 25ยฐc) provides clean evaporation at body temperature. the cyclic ring structure provides lower boiling point than equivalent linear dimethicone, enabling faster evaporation while the ring conformation maintains the silicone's low surface energy for smooth application.
Typically Found In: Primers,antiperspirants,sunscreens
TECHNICAL DETAILS
Primary Category: Functional ingredient โ emollient
Secondary Functions: Barrier sealing,softening
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 1%โ50%
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Plant-derived, synthetic or animal-derived. verify source.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 1/5 โ low; formulation-dependent
Sensitivity Concerns: Non-irritating.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Humectants,ceramides,actives as carrier
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Cyclopentasiloxane (d5) and cyclohexasiloxane (d6) are under eu regulatory review for potential environmental persistence (pbt assessment) โ formulators should monitor eu regulation 2018/35 implementation for restrictions in wash-off products.
Last Verified: Cosing database,eu cyclosiloxane regulatory review
Primary Sources: 2026-03-12
Dimethicone
Common Name(s): Pdms,polydimethylsiloxane,silicone fluid
CAS Number: 9006-65-9
DESCRIPTION
What It Does: Provides silicone-characteristic silky feel and skin protection with adjustable viscosity.
Why It's Used: The benchmark cosmetic silicone โ sets the gold standard for silky application feel, spreadability, and skin protection in virtually all skin care categories.
How It Works: Polydimethylsiloxane chain flexibility provides extremely low surface tension and high spreadability. inert si-o backbone provides chemical stability and excellent skin tolerance. occlusive film formation reduces tewl. higher viscosity grades provide more intense conditioning.
Typically Found In: Moisturizers,foundations,primers,sunscreens โ nearly universal
TECHNICAL DETAILS
Primary Category: Functional ingredient โ polydimethylsiloxane
Secondary Functions: Barrier sealing,softening
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%โ30%
SOURCING & ETHICS
Vegan Status: Yes โ synthetic
Halal Status: Yes
Source Notes: Plant-derived, synthetic or animal-derived. verify source.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 1/5 โ low; formulation-dependent
Sensitivity Concerns: Non-irritating.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Humectants,ceramides,actives as carrier
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Dimethicone's exceptional silky feel arises from its very low intermolecular attractive forces (weak van der waals forces due to non-polar methyl groups) that allow silicone chains to slide freely over skin. the coefficient of kinetic friction for pdms against skin (~0.04) is among the lowest of any cosmetic material โ explaining why even small amounts transform product feel.
Last Verified: Cosing database,cir safety assessment
Primary Sources: 2026-03-12