
Highlights
WHAT IS IT?
Serum with 11 ingredients
FEATURES
100% natural Salicylic Acid Booster, exfoliating beta hydroxy acid (BHA), blemish-buster, extracted from White Willow Bark and Wintergreen
BEST FOR
Oily, combination and blemish-prone skin
CHECKS
Fragrance-free
Who Is It For?
Adults Women And MenWhat Does It Help With?
Clarifying Congested Skin Exfoliating SmoothingBudget
Mid-rangeHow To Use
Which routine should it be used in?
Instructions:
Key Information
What Pai Skincare Says
Product Description:
All-natural booster drops for blemish-prone skin
About the Brand:
Ingredients Overview
Ingredients List
AQUA, CHAMOMILLA RECUTITA FLOWER WATER, PENTYLENE GLYCOL, ALCOHOL DENAT., SALIX ALBA BARK EXTRACT (willow), GLYCERIN, SALICYLIC ACID, INULIN, XANTHAN GUM, FRUCTOSE, SODIUM HYDROXIDE
Key Ingredients
Salicylic Acid, White Willow Bark Extract, Chamomile Water
Ingredients Details
Alcohol Denat.
Common Name(s): Alcohol denat.,denatured ethanol,solvent antimicrobial astringent
CAS Number: N/a
DESCRIPTION
What It Does: Alcohol denat. dissolves oil-soluble and water-soluble cosmetic actives, provides rapid antimicrobial activity at concentrations above 60โ70% by denaturing microbial proteins, delivers a refreshing cooling sensation through evaporative cooling on skin, and temporarily enhances the penetration of topical actives by transiently disrupting the stratum corneum lipid bilayer organisation.
Why It's Used: Formulators choose alcohol denat. for its irreplaceable combination of solvent power, antimicrobial activity, and penetration-enhancing properties. no other cosmetic solvent simultaneously provides the cooling sensory experience of alcohol (from evaporative cooling at the skin surface), the immediate antimicrobial activity required for sanitisers (from protein denaturation above 60%), and the transient sc lipid disruption that improves active ingredient delivery (essential in actives-rich toners and essences). for denatured alcohol specifically, denaturing agents (typically 5% isopropanol or bitrex) prevent consumption without affecting cosmetic function.
How It Works: Alcohol denat. works through multiple mechanisms depending on concentration: (1) solvent action โ alcohol's hydroxyl group provides hydrogen bonding with water while the short alkyl chain provides interaction with organic solutes, enabling dissolution of both hydrophilic and moderately lipophilic cosmetic actives in a single solvent; (2) antimicrobial โ above 60% concentration, ethanol denatures microbial proteins by disrupting non-covalent bonds maintaining protein secondary and tertiary structure โ the alcohol molecules intercalate between protein chains, disrupting the hydrophobic interactions and hydrogen bonds that maintain enzyme active site geometry. this non-specific protein denaturation is immediately bactericidal and virucidal with no resistance mechanism possible; (3) sc penetration enhancement โ at lower concentrations (5โ30%), ethanol transiently fluidises the sc lipid bilayer by intercalating between the ordered lipid lamellae, disrupting the crystal packing and increasing lipid bilayer fluidity. this transient fluidisation increases the diffusion coefficient of co-applied actives through the sc for up to 30 minutes post-application; (4) astringency โ alcohol's protein precipitating action at the skin surface contracts superficial proteins, temporarily tightening pores and reducing oiliness.
Typically Found In: Toners,hand sanitisers,actives serums
TECHNICAL DETAILS
Primary Category: Active ingredient โ cosmetic active
Secondary Functions: Skin conditioning
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 5%โ95%
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Well-tolerated by most skin types.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Good safety profile at recommended concentrations. ewg score: 1โ2.
Works Well With: Standard skincare actives
Avoid Combining With: No known significant incompatibilities
SCIENTIFIC NOTE
Ethanol concentration-dependent antimicrobial efficacy: below 40% โ minimal bactericidal effect (insufficient protein denaturation); 40โ60% โ bacteriostatic, not bactericidal; 60โ70% โ peak bactericidal efficacy against both enveloped and non-enveloped viruses and vegetative bacteria (optimal water content maintains protein hydration required for denaturation to proceed); 80โ90% โ remains effective but slightly reduced from decreased water activity; 95โ100% โ reduced efficacy (insufficient water for protein denaturation). the 70% 'sweet spot' for sanitisers reflects this concentration-efficacy peak, not a formulation convenience.
Last Verified: Cosing database,alcohol denat. ethanol solvent antimicrobial review
Primary Sources: 2026-03-12
Chamomilla Recutita Flower Water
Common Name(s): Chamomilla recutita flower extract
DESCRIPTION
What It Does: Provides antioxidant protection, soothing anti-inflammatory effects, and skin-conditioning benefits through plant-derived polyphenols and phytochemicals.
Why It's Used: Plant extracts concentrate bioactive phytochemicals evolved for environmental protection โ uv, microbial, and oxidative stressors โ that translate to skin benefits.
How It Works: Polyphenols (flavonoids, phenolic acids) inhibit nf-ฮบb-mediated inflammatory signaling, scavenge reactive oxygen species through electron donation, and chelate pro-oxidant metal ions to reduce oxidative skin damage.
Typically Found In: Serums,toners,moisturizers,masks,essences
TECHNICAL DETAILS
Primary Category: Botanical extracts
Secondary Functions: Antioxidant,anti-inflammatory
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1โ10%
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Plant-derived extract; no animal components.
SKIN COMPATIBILITY
Irritancy Rating: 1
Comedogenicity Rating: 0
Sensitivity Concerns: Low sensitization potential at recommended use concentrations.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Well-characterized cosmetic ingredient with established safety profile. generally non-irritating at typical use concentrations. suitable for leave-on and rinse-off cosmetics.
Works Well With: Niacinamide,hyaluronic acid,vitamin c,ceramides
Avoid Combining With: Strong oxidizing agents
SCIENTIFIC NOTE
Plant secondary metabolites (flavonoids, terpenes, phenolic acids) are biosynthesized as defense compounds against uv, herbivores, and pathogens. their anti-inflammatory activity typically derives from competitive inhibition of cox-2 and 5-lox enzymes (ic50 1โ50 ยตm), while antioxidant activity involves single electron transfer (set) and hydrogen atom transfer (hat) mechanisms with structure-dependent rate constants.
Last Verified: Cosing eu database; pcpc cosmetic ingredient safety reviews; phytochemical and ethnobotanical literature
Primary Sources: 2025-01-15
Fructose
Common Name(s): Levulose,d-fructose,fruit sugar
CAS Number: 57-48-7
DESCRIPTION
What It Does: Provides natural fruit sugar humectant moisture retention with gentle soothing properties.
Why It's Used: Natural-origin humectant for clean beauty formulations with appealing fruit-derived provenance.
How It Works: Five hydroxyl groups provide strong water binding. slightly higher hygroscopicity than glucose due to fructose ring configuration. soothing activity via mild anti-inflammatory activity of fruit sugar derivatives.
Typically Found In: Natural moisturizers,clean beauty hydrators
TECHNICAL DETAILS
Primary Category: Active ingredient โ fruit sugar humectant
Secondary Functions: Natural sugar humectant,soothing
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 1%โ10%
SOURCING & ETHICS
Vegan Status: Yes โ from fruit (plant sources)
Halal Status: Yes
Source Notes: Synthetic or naturally derived. excellent aqueous solubility.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; suitable for all skin types.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Ceramides,emollients,occlusives,glycerin,hyaluronic acid
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Fructose's ring form (furanose, 5-membered) provides all five hydroxyl groups in a more hydrophilic spatial arrangement than glucose (pyranose, 6-membered), contributing to fructose's slightly superior hygroscopicity over glucose โ explaining its preference as a cosmetic humectant among monosaccharides.
Last Verified: Cosing database,cir safety assessment
Primary Sources: 2026-03-12
Glycerin
Common Name(s): Glycerol,glycerine,1,2,3-propanetriol
CAS Number: 56-81-5
DESCRIPTION
What It Does: Glycerin pulls water from the environment and deeper skin layers into the outer skin layer (epidermis), boosting moisture levels and keeping skin soft, smooth, and plump.
Why It's Used: It is used in virtually every moisturizer, serum, and cleanser because it is highly effective at hydrating skin, is well-tolerated by all skin types, and enhances the texture and spreadability of formulations.
How It Works: As a humectant, glycerin forms hydrogen bonds with water molecules, trapping them in the skin. it also reinforces the skin barrier by integrating into lipid structures between skin cells.
Typically Found In: Moisturizers,serums,cleansers,toners,sheet masks,sunscreens,body lotions,shampoos,conditioners
TECHNICAL DETAILS
Primary Category: Humectant
Secondary Functions: Skin barrier support,emollient,solvent
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 1%โ30% (typical: 3โ10%)
SOURCING & ETHICS
Vegan Status: Yes โ plant-derived (coconut, soy, palm) or synthetic
Halal Status: Yes โ when plant-derived or synthetic; verify source with supplier
Source Notes: Derived from plant oils via hydrolysis or saponification; synthetic versions also available. palm-derived glycerin carries sustainability concerns.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low; non-irritating at all standard concentrations
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Extremely rare allergic reactions; generally safe for all skin types including sensitive and baby skin
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Widely recognized as safe. ewg hazard score: 1. no significant concerns for irritation, sensitization, or toxicity at typical concentrations (up to 50%).
Works Well With: Hyaluronic acid,ceramides,niacinamide,panthenol,urea,peptides,retinol,ahas/bhas
Avoid Combining With: No known incompatibilities at standard concentrations
SCIENTIFIC NOTE
Glycerin is an endogenous skin component found naturally in the stratum corneum. aquaporin-3 channels in keratinocytes facilitate glycerin transport, making it integral to natural skin hydration pathways.
Last Verified: Cosing database,cir safety assessment,ewg skin deep,inci decoder
Primary Sources: 2026-03-12