Swiss Perfection RS-28 Cellular Rejuvenation Serum

DESCRIPTION

What It Does: Absorbs or reflects uv radiation, preventing uv-induced dna damage, photo-oxidative stress, and premature skin aging.

Why It's Used: Uv filters are the active ingredients in sun protection — without them, formulations cannot make spf claims or prevent solar-induced skin damage.

How It Works: The uv-absorbing chromophore undergoes photoexcitation by uv photons, then dissipates the absorbed energy through thermal relaxation (chemical filters) or photon scattering/reflection (physical filters), preventing photon penetration to skin cells.

Typically Found In: Sunscreens,moisturizers with spf,foundations with spf

TECHNICAL DETAILS

Primary Category: Uv filters

Secondary Functions: Skin-protecting

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.5–25% (within regulatory limits)

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Synthetic uv filter; no animal components.

SKIN COMPATIBILITY

Irritancy Rating: 1

Comedogenicity Rating: 0

Sensitivity Concerns: Contact allergy to uv filters occurs in approximately 1–3% of the general population; patch testing recommended for those with known photosensitivity.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Regulatory approval required per market (eu annex vi, fda otc monograph, etc.). generally non-irritating at approved concentrations.

Works Well With: Other uv filters,antioxidants,emollients

Avoid Combining With: Incompatible filter combinations (photodegradation); check regulatory approvals per region

SCIENTIFIC NOTE

Uv filters operate through two mechanisms: organic/chemical filters absorb uv photons through electronic excitation (π→π* transitions in conjugated systems), then dissipate energy via thermal relaxation; inorganic/physical filters (tio2, zno) scatter and reflect photons through mie scattering (particle size 50–300 nm) and band gap absorption. spf is measured in vivo (iso 24444) as the ratio of minimal erythema doses with and without sunscreen.

Last Verified: Cosing eu database; pcpc cosmetic ingredient safety reviews; eu cosmetics regulation annex vi; iso 24444 (in vivo spf testing)

Primary Sources: 2025-01-15

DESCRIPTION

What It Does: Provides natural warm-brown colour from heat-treated sugar for natural cosmetics.

Why It's Used: Natural brown colorant with food-grade safety credentials for clean beauty formulations requiring warm brown or amber shades.

How It Works: Complex mixture of pyranose-ring condensation products from heat-treated sugars. 5-hmf and melanoidin polymers provide brown colour. ph-stable in acidic formulations. soluble in water and lower alcohols.

Typically Found In: Natural cosmetics,bronzers,hair products

TECHNICAL DETAILS

Primary Category: Colorant – natural brown dye

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.01%–5%

SOURCING & ETHICS

Vegan Status: Yes – from sucrose, glucose (plant sugars)

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Caramel's colour develops through the maillard reaction between reducing sugars and amino acids at elevated temperatures, creating a complex mixture of coloured polymer (melanoidin) and small molecule chromophores. unlike single-compound dyes with defined absorption spectra, caramel's broad-spectrum absorption from multiple chromophores provides a naturally warm, complex brown impossible to replicate with a single synthetic dye.

Last Verified: Cosing database,fda 21 cfr color additives

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides antimicrobial skin conditioning with deodorant activity and preservation system enhancement.

Why It's Used: Multifunctional clean beauty preservation active — ethylhexylglycerin provides antimicrobial, deodorant, and skin conditioning in a single ingredient accepted in most natural cosmetic certification schemes.

How It Works: Glycerol ether provides antimicrobial via bacterial membrane phospholipid disruption. deodorant activity via reduction of underarm lipase enzyme activity (similar mechanism to triethyl citrate). skin conditioning from glycerol humectant component. synergistic with phenoxyethanol and diols.

Typically Found In: Natural preservation systems,deodorants,skin conditioning products

TECHNICAL DETAILS

Primary Category: Functional ingredient – antimicrobial glycerol ether

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–0.5%

SOURCING & ETHICS

Vegan Status: Yes – synthetic

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Ethylhexylglycerin's deodorant mechanism is pharmacologically identical to triethyl citrate: both inhibit skin surface microbial lipase enzymes that convert odourless triglycerides to odorous free fatty acids. the glycerol ether structure of ethylhexylglycerin, combined with the 2-ethylhexyl chain, provides lipase inhibition similar to ester-based lipase inhibitors from a different chemical class.

Last Verified: Cosing database,schülke sensiva sc 10 technical data,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Glycerin pulls water from the environment and deeper skin layers into the outer skin layer (epidermis), boosting moisture levels and keeping skin soft, smooth, and plump.

Why It's Used: It is used in virtually every moisturizer, serum, and cleanser because it is highly effective at hydrating skin, is well-tolerated by all skin types, and enhances the texture and spreadability of formulations.

How It Works: As a humectant, glycerin forms hydrogen bonds with water molecules, trapping them in the skin. it also reinforces the skin barrier by integrating into lipid structures between skin cells.

Typically Found In: Moisturizers,serums,cleansers,toners,sheet masks,sunscreens,body lotions,shampoos,conditioners

TECHNICAL DETAILS

Primary Category: Humectant

Secondary Functions: Skin barrier support,emollient,solvent

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%–30% (typical: 3–10%)

SOURCING & ETHICS

Vegan Status: Yes – plant-derived (coconut, soy, palm) or synthetic

Halal Status: Yes – when plant-derived or synthetic; verify source with supplier

Source Notes: Derived from plant oils via hydrolysis or saponification; synthetic versions also available. palm-derived glycerin carries sustainability concerns.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low; non-irritating at all standard concentrations

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Extremely rare allergic reactions; generally safe for all skin types including sensitive and baby skin

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Widely recognized as safe. ewg hazard score: 1. no significant concerns for irritation, sensitization, or toxicity at typical concentrations (up to 50%).

Works Well With: Hyaluronic acid,ceramides,niacinamide,panthenol,urea,peptides,retinol,ahas/bhas

Avoid Combining With: No known incompatibilities at standard concentrations

SCIENTIFIC NOTE

Glycerin is an endogenous skin component found naturally in the stratum corneum. aquaporin-3 channels in keratinocytes facilitate glycerin transport, making it integral to natural skin hydration pathways.

Last Verified: Cosing database,cir safety assessment,ewg skin deep,inci decoder

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides non-ionic thickening compatible with anionic surfactants and electrolyte-containing formulations.

Why It's Used: Non-ionic cellulose thickener for surfactant systems where anionic/cationic thickener incompatibility is a concern.

How It Works: Hydroxyethyl substitution disrupts cellulose crystallinity enabling water solubility. non-ionic nature provides compatibility with anionic, cationic, and amphoteric surfactants. pseudoplastic rheology provides shear-thinning for dispensing. film formation from cellulose backbone.

Typically Found In: Shampoos,body washes,clear gels,surfactant systems

TECHNICAL DETAILS

Primary Category: Functional ingredient – cellulose thickener

Secondary Functions: Tewl reduction,skin plumping

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–3%

SOURCING & ETHICS

Vegan Status: Yes – from cellulose (plant)

Halal Status: Yes

Source Notes: Synthetic or naturally derived. excellent aqueous solubility.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; suitable for all skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Ceramides,emollients,occlusives,glycerin,hyaluronic acid

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Hydroxyethylcellulose's non-ionic character is its primary differentiator from anionic carboxymethylcellulose – the absence of ionizable groups means hec maintains stable viscosity across ph 2-12 and at high electrolyte concentrations where carboxymethylcellulose destabilizes. this ionic independence makes hec the preferred cellulose thickener for acidic and salt-containing formulations.

Last Verified: Cosing database,ashland hec technical data,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides the defining fresh citrus fragrance note alongside solvent and antimicrobial properties.

Why It's Used: The citrus industry's primary fragrance compound and the most abundant terpene in essential oils – limonene provides the clean, universally appealing fresh citrus scent character.

How It Works: D-limonene activates trpv1 mildly at high concentrations. antimicrobial via membrane disruption. solvent for oils and lipophilic compounds. cleaning via emulsification of lipid soils.

Typically Found In: Citrus-scented products,cleaning products,fragrance compounds

TECHNICAL DETAILS

Primary Category: Fragrance component – cyclic monoterpene

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.001%–3%

SOURCING & ETHICS

Vegan Status: Yes – from citrus peel essential oils

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Eu cosmetics regulation: declared fragrance allergen. oxidises to sensitising compounds (limonene hydroperoxides) on air exposure – use with antioxidant stabilisers. ifra guidelines apply.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Limonene's sensitisation risk arises not from limonene itself but from its autooxidation products (limonene-1,2-epoxide and limonene hydroperoxides) formed on air exposure. fresh limonene has low sensitisation potential, but air-oxidised limonene's hydroperoxide products are potent skin sensitisers. this explains why oxidation-stabilised formulations (with bht or other antioxidants) are required to manage limonene safety.

Last Verified: Cosing database,ifra standards,bråred christensson et al. limonene oxidation study

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides the most common natural floral-citrus fragrance note with additional anti-inflammatory properties.

Why It's Used: The most abundant fragrance terpene in nature – linalool forms the primary scent character of lavender, responsible for lavender's documented aromatherapy calming effects.

How It Works: Monoterpene alcohol activates gaba-a receptors for anti-anxiety activity (same receptor as benzodiazepines). inhibits glutamate-induced excitotoxicity. antimicrobial via membrane disruption. anti-inflammatory via nf-kb inhibition.

Typically Found In: Virtually all fragranced cosmetics

TECHNICAL DETAILS

Primary Category: Fragrance component – tertiary terpene alcohol

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.001%–3%

SOURCING & ETHICS

Vegan Status: Yes – from lavender, coriander, bergamot

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Eu cosmetics regulation: declared fragrance allergen on label when >0.001% (leave-on) or >0.01% (rinse-off). ifra guidelines apply.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Linalool's gaba-a receptor activation provides a pharmacological basis for lavender aromatherapy's documented anxiolytic effects. the same receptor modulation used by benzodiazepine drugs (such as diazepam) is activated by inhaled linalool vapor, providing receptor-mediated calming without the tolerance and dependence associated with pharmaceutical gaba-a modulators.

Last Verified: Cosing database,ifra standards,elisabetsky et al. linalool gaba study

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Prevents microbial contamination and spoilage in cosmetic formulations.

Why It's Used: The benchmark cosmetic preservative – eu-permitted up to 1%, effective against virtually all cosmetically relevant microorganisms, and excellent tolerability.

How It Works: Phenol ring provides broad antimicrobial activity via disruption of bacterial and fungal cell membranes and inhibition of enzymatic activity. effective against gram-positive and gram-negative bacteria, yeasts (candida), and molds (aspergillus). activity ph range: 3-9.

Typically Found In: All cosmetic formulations as primary preservative

TECHNICAL DETAILS

Primary Category: Functional ingredient – broad-spectrum preservative

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–1% (eu max 1%)

SOURCING & ETHICS

Vegan Status: Yes – synthetic

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Eu cosmetics regulation max 1%. sccs assessed as safe at ≤1%. avoid use around eyes in baby products per some country regulations. ewg score: 4.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Phenoxyethanol's widespread adoption as the primary cosmetic preservative followed the phaseout of parabens from many formulations in the 2000s-2010s. despite having a comparable or better safety profile to parabens, it is often cited in 'free-from' formulations – a consumer perception issue rather than a scientific safety concern.

Last Verified: Cosing database,sccs opinion on phenoxyethanol,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Delivers characteristic cosmetic function at recommended use concentration.

Why It's Used: Selected for functional contribution and formulation compatibility supported by cosmetic science and regulatory safety data.

How It Works: Works through the mechanism of its molecular class — physicochemical or biological interaction with skin proteins, lipids, or receptors as documented in peer-reviewed cosmetic literature.

Typically Found In: Skin care formulations

TECHNICAL DETAILS

Primary Category: Active ingredient – cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–10%

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Ppg-26-buteth-26 has an established safety and efficacy profile within the cosmetic regulatory framework at standard use concentrations.

Last Verified: Cosing database,ppg-26-buteth-26 technical literature

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Tocopherol neutralizes free radicals that damage skin cells, protects cell membranes from lipid peroxidation, moisturizes, and helps maintain a healthy skin barrier.

Why It's Used: It is used as both a skin-active antioxidant and a formulation stabilizer (preventing oxidation of other ingredients). it has decades of safety and efficacy evidence and works synergistically with vitamin c.

How It Works: As a chain-breaking antioxidant, tocopherol donates hydrogen atoms to interrupt lipid peroxidation chain reactions. it is regenerated by vitamin c (ascorbic acid) in the vitamins c+e antioxidant cycle, creating a more durable antioxidant defense.

Typically Found In: Moisturizers,serums,oils,sunscreens,eye creams,lip balms,antioxidant formulations,haircare products

TECHNICAL DETAILS

Primary Category: Active ingredient – antioxidant/vitamin e

Secondary Functions: Emollient,formulation stabilizer,barrier support

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–1% (typical: 0.1–0.5% as active; higher as formulation antioxidant)

SOURCING & ETHICS

Vegan Status: Yes – plant-derived (soybean, sunflower, wheat germ oil) or synthetic

Halal Status: Yes – plant-derived or synthetic

Source Notes: Natural d-alpha-tocopherol is derived from plant oils and is more bioactive. synthetic dl-alpha-tocopherol is less expensive. tocopherol acetate (tocopheryl acetate) is the more stable ester form.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low; rare contact sensitivity reported

Comedogenicity Rating: 2/5 – mildly comedogenic at higher concentrations; formulation-dependent

Sensitivity Concerns: A small percentage of people report contact sensitization to tocopherol, particularly with leave-on products. comedogenicity risk is higher in oil-heavy formulations.

Safe for Sensitive Skin: Generally yes; perform patch test if history of vitamin e sensitivity

SAFETY & COMPATIBILITY

Safety Profile: Very safe; widely used. ewg hazard score: 2–3 (depending on concentration). no significant systemic concerns from topical use.

Works Well With: Ascorbic acid (vitamin c) – synergistic antioxidant pair,ferulic acid – stabilizes and boosts both c and e,ceramides,spf,retinol

Avoid Combining With: Very high concentrations of benzoyl peroxide may oxidize tocopherol; potential comedogenicity concerns in acne-prone skin when in heavy oil bases

SCIENTIFIC NOTE

The combination of vitamin c, vitamin e, and ferulic acid (the 'ce ferulic' formulation) provides fourfold photoprotection against uv-induced free radical damage – a synergy documented in landmark research by pinnell et al.

Last Verified: Cosing database,cir safety assessment,pinnell et al. (2005) journal of investigative dermatology,efsa panel on food additives

Primary Sources: 2026-03-12