
Highlights
WHAT IS IT?
5-in-1 Daily Skin Defence serum with bio-active ingredients
FEATURES
Moisturizing serum reduces fine lines and wrinkles, contains resveratrol, hyaluronic acid, allantoin, moringa, witch hazel, retinol, vitamin B3, slows aging effects, combats dull skin tone and discoloration, provides hydration, keeps skin healthy and youthful, free from parabens, alcohol, phthalates, mineral oil and toxins
BEST FOR
normal
CHECKS
Free from parabens, alcohol, phthalates, mineral oil, toxins
Who Is It For?
What Does It Help With?
Reduces Fine Lines And Wrinkles Dull Skin Tone Discoloration Loss Of Firmness Age SpotsBudget
Mid-range ($30-$75)How To Use
Which routine should it be used in?
Instructions:
Key Information
What Nykaa E retail limited Says
Product Description:
The Skin Story 5-in-1 Daily Skin Defence goes beyond moisturizing to deliver an innovative mix of research-proven ingredients known to reduce the appearance of fine lines, wrinkles, dull skin tone, discoloration and loss of firmness. The unique and scientifically proven complex of bio-active ingredients like resveratrol, hyaluronic acid, allantoin, moringa, witch hazel, retinol and vitamin B3 has been studied and is known to keep your skin healthy, young and hydrated. Features: Moisturizing serum that reduces the appearance of fine lines and wrinkles making the skin look youthful, Formulated with bio-active ingredients like resveratrol, hyaluronic acid, allantoin, moringa, witch hazel, retinol and vitamin B3, Slows down the effects of aging and gives skin an ageless glow, Combats dull skin tone and discoloration of the skin with a burst of hydration, Keeps skin healthy, youd and hydrated, Free from parabens, alcohol, phthalates, mineral oil and toxins.
About the Brand:
Ingredients Overview
Ingredients List
resveratrol,hyaluronic-acid,retinol
Key Ingredients
resveratrol,hyaluronic acid,retinol
Ingredients Details
Resveratrol
Common Name(s): Trans-resveratrol,3,5,4'-trihydroxystilbene,red wine antioxidant
CAS Number: 501-36-0
DESCRIPTION
What It Does: Provides potent antioxidant protection, activates anti-aging sirtuin pathways, and reduces inflammation.
Why It's Used: Premium anti-aging antioxidant targeting sirt1-mediated longevity pathways alongside strong direct antioxidant and anti-inflammatory activity.
How It Works: Direct free radical scavenging via hydroxystilbene phenolic groups. activates sirt1 deacetylase, promoting mitochondrial biogenesis and dna repair. inhibits nf-kb for anti-inflammatory effects. may block tyrosinase for mild brightening.
Typically Found In: Premium anti-aging serums,antioxidant complexes,anti-inflammatory products
TECHNICAL DETAILS
Primary Category: Active ingredient โ stilbene antioxidant
Secondary Functions: Sirtuin activation,anti-inflammatory,longevity pathway
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%โ1%
SOURCING & ETHICS
Vegan Status: Yes โ plant-derived or synthetic
Halal Status: Yes
Source Notes: Extracted from japanese knotweed (polygonum cuspidatum), grape skins, or synthesized. trans-form is bioactive; cis-form less active.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Generally well-tolerated; rare reports of contact sensitization at high concentrations.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Resveratrol's sirt1 activation promotes mitochondrial biogenesis via pgc-1ฮฑ, potentially reversing age-related mitochondrial dysfunction in skin cells โ the same longevity pathway activated by caloric restriction in model organisms.
Last Verified: Cosing database,baur & sinclair resveratrol review,cir safety assessment
Primary Sources: 2026-03-12
Retinol
Common Name(s): Vitamin a,all-trans retinol,(all-e)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol
CAS Number: 68-26-8
DESCRIPTION
What It Does: Retinol accelerates skin cell turnover, stimulates collagen production, reduces fine lines and wrinkles, fades hyperpigmentation, and helps normalize pore size.
Why It's Used: It is the most evidence-backed anti-aging ingredient available without a prescription. it provides comprehensive skin renewal benefits that no other single cosmetic ingredient can match.
How It Works: Retinol is converted in the skin to retinoic acid, which binds to retinoid receptors in cell nuclei. this activates gene expression changes that accelerate cell turnover, boost collagen synthesis, and inhibit matrix metalloproteinases (collagen-degrading enzymes).
Typically Found In: Night creams,serums,eye creams,targeted treatment products,anti-aging formulations
TECHNICAL DETAILS
Primary Category: Active ingredient โ vitamin a derivative
Secondary Functions: Exfoliating,anti-acne,brightening
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.025%โ1% (otc); start at low concentrations and build up slowly
SOURCING & ETHICS
Vegan Status: Conditional โ can be animal-derived (fish liver, egg yolk) or synthetic; verify source
Halal Status: Conditional โ verify source; synthetic retinol is halal
Source Notes: Cosmetic retinol is predominantly synthetically manufactured. some natural sources include fish liver oils. synthetic is preferred for purity and sustainability.
SKIN COMPATIBILITY
Irritancy Rating: 3/5 โ moderate; can cause dryness, peeling, redness, especially during adjustment period (retinization)
Comedogenicity Rating: 0/5 โ non-comedogenic; actually helps clear pores
Sensitivity Concerns: Retinization period: 2โ6 weeks of potential dryness, flaking, and sensitivity. photosensitizing โ must use spf when using retinol. avoid during pregnancy.
Safe for Sensitive Skin: Use with caution โ start at 0.025%, buffer with moisturizer, use every 2โ3 nights initially
SAFETY & COMPATIBILITY
Safety Profile: Safe for general use at otc concentrations. not recommended during pregnancy. avoid with waxing. use spf daily. ewg hazard score: varies by concentration.
Works Well With: Niacinamide (soothes irritation),peptides,ceramides,hyaluronic acid,spf (mandatory)
Avoid Combining With: Benzoyl peroxide (may inactivate retinol),ahas/bhas (when new to retinol โ overexfoliation risk),vitamin c (use at different times)
SCIENTIFIC NOTE
Retinol is approximately 20 times less potent than prescription tretinoin (retinoic acid) but significantly better tolerated. the conversion rate of retinol to retinoic acid in skin is the rate-limiting step in its efficacy.
Last Verified: Cosing database,cir safety assessment,journal of investigative dermatology,kligman et al. studies
Primary Sources: 2026-03-12