Ultimune Power Infusing Serum

Shiseido

Ultimune Power Infusing Serum

Ultimune Power Infusing Serum

Shiseido

ultimune-power-infusing-serum

Serum

9605087002917

Morning or Evening?

Morning
Evening
Both

How often will you use this product?

Everyday
Every other day
Every 3 days
Every 4 days
Every 5 days
Every 6 days
Once a week
Twice a week
On specific days
As needed
On rotation

Notes

Add to Routine
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Compatibility Score

0%

Microbiome
Ingredients
Biological
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How It Fits Into Your Skincare Routine

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Highlights

WHAT IS IT?

Antioxidant face serum

FEATURES

Lightweight texture, delivers visible changes in 3 days

BEST FOR

Dry skin

CHECKS

Oil-free, parabens-free, sulfates-free

Who Is It For?

Not Specified Likely For Adults

What Does It Help With?

Improves Radiance Resilience And Smoothness Of Skin

Budget

Premium

How To Use

Which routine should it be used in?

Morning
Evening
 
Cleanse
Tone
Eyecare
Serum
Moisturize
Suncare
 

Instructions:

Use Ultimune after cleansing and softening skin, but before applying other serums or moisturizers. Pump twice onto fingertips and smooth evenly over face and neck. Use Ultimune twice daily, morning and evening.

Key Information

Vegan
Cruelty-free
Sensitive-safe
Non-comedogenic
Hypoallergenic
Microbiome-safe
Preservative-free
Eco-friendly
Pregnancy-safe
Oil-free

What Shiseido Says

Product Description:

A potent antioxidant face serum that delivers 3 visible changes in 3 days: radiance, resilience, and smoothness*.

About the Brand:

From its humble beginnings as Japan's first Western-style pharmacy, Shiseido has evolved into a global skincare powerhouse. With a rich history rooted in pharmacology, Shiseido brings you technologically advanced skincare solutions that are revered by experts worldwide. Experience over a century of beauty innovation with every application.

Ingredients Overview

Ingredients List

Water, Alcohol Denat, Glycerin, Dimethicone, Butylene Glycol, PEG/โ€‹PPG-17/โ€‹4 Dimethyl Ether, Triethylhexanoin, Ammonium Acryloyldimethyltaurate/โ€‹Beheneth-25 Methacrylate Crosspolymer, Phenoxyethanol, PEG-14M, Methylparaben, Tocopheryl Acetate, PEG/โ€‹PPG-14/โ€‹7 Dimethyl Ether, Rosa Damascena Flower Water, Acrylates/โ€‹C10-30 Alkyl Acrylate Crosspolymer, Fragrance, Disodium EDTA, Potassium Hydroxide, Silica, Isoceteth-10, Linalool, Ginkgo Biloba Leaf Extract (Ginkgo Biloba), Geraniol, Citronellol, Sodium Carboxymethyl Beta-Glucan, BHT, Thymus Serpillum Extract, Perilla Ocymoides Leaf Extract, Sodium Bicarbonate

Key Ingredients

Tocopheryl Acetate, Glycerin

Ingredients Details

Tocopheryl Acetate

Common Name(s): Vitamin e acetate,alpha-tocopherol acetate,dl-alpha-tocopheryl acetate

CAS Number: 7695-91-2

DESCRIPTION

What It Does: Provides stable vitamin e delivery with antioxidant activity after esterase hydrolysis in skin.

Why It's Used: The formulation-stable vitamin e โ€” tocopheryl acetate's ester protection prevents oxidative degradation during shelf life while releasing active tocopherol in skin for equivalent biological activity.

How It Works: Acetate ester blocks the phenolic oh group responsible for oxidation and radical scavenging. skin esterases cleave acetate bond releasing free tocopherol. released tocopherol provides lipid peroxyl radical scavenging in cell membranes. also provides direct emollient and skin conditioning.

Typically Found In: Moisturisers,sunscreens,anti-aging products โ€” extremely widespread

TECHNICAL DETAILS

Primary Category: Active ingredient โ€“ stable vitamin e ester

Secondary Functions: Free radical scavenging,anti-aging

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%โ€“5%

SOURCING & ETHICS

Vegan Status: Conditional โ€“ natural from vegetable oils (soy, sunflower); synthetic dl-form

Halal Status: Yes

Source Notes: Plant-derived extract or synthetic.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Non-irritating; well-tolerated.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: The d-alpha-tocopheryl acetate (natural isomer) is biologically superior to dl-alpha-tocopheryl acetate (racemic synthetic) for skin antioxidant activity. ingredient label d- vs dl- prefix identifies natural vs synthetic origin.

Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Tocopheryl acetate's conversion to active tocopherol in skin is quantitatively efficient: skin esterase activity is sufficient to cleave 60-80% of applied tocopheryl acetate within 24 hours of application. however, the conversion rate varies with skin condition (eczematous or barrier-compromised skin has reduced esterase activity), meaning tocopheryl acetate efficacy may be reduced precisely in the skin conditions that most need antioxidant support.

Last Verified: Cosing database,cir safety assessment

Primary Sources: 2026-03-12

Water

Common Name(s): Water,purified water,deionised water,inci water

CAS Number: 7732-18-5

DESCRIPTION

What It Does: Provides the universal solvent and vehicle for water-soluble actives and the continuous phase of all o/w emulsions.

Why It's Used: The most essential cosmetic ingredient โ€” aqua (water) is listed first on virtually all water-containing cosmetic inci labels as the highest-concentration ingredient, serving as the foundation of the global cosmetics industry.

How It Works: Acts as solvent for all water-soluble ingredients (glycols, amino acids, water-soluble actives). forms the continuous external phase of o/w emulsions (lotions, creams, serums). provides aqueous environment for enzymatic and chemical reactions between actives. ph adjustment medium.

Typically Found In: Virtually all cosmetic products โ€” the most universal cosmetic ingredient globally

TECHNICAL DETAILS

Primary Category: Functional ingredient โ€“ water

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: Varies widely โ€” up to 95% in some toners and serums

SOURCING & ETHICS

Vegan Status: Yes โ€“ water (deionised/purified)

Halal Status: Yes

Source Notes: Cosmetic-grade water is purified (deionised, distilled, or ro filtered) to prevent mineral content interference with formulation stability. european pharmacopoeial water (aqua purificata ph. eur.) is the quality standard for pharmaceutical and high-end cosmetic formulations.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ non-irritant

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1โ€“2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Water's position as the first inci ingredient on most cosmetic labels reflects the regulatory requirement to list ingredients in descending concentration order โ€” meaning water is the most abundant ingredient in the majority of cosmetic products. the fundamental role of water as the universal cosmetic solvent and vehicle makes it simultaneously the most important cosmetic ingredient and the one that requires the most sophisticated formulation chemistry to control โ€” every emulsifier, thickener, preservative, and ph adjuster exists primarily to manage water's interaction with other ingredients in formulation.

Last Verified: Cosing database,eu cosmetics regulation 1223/2009 inci requirements,ph. eur. aqua purificata monograph

Primary Sources: 2026-03-12