Uriage Depiderm 20% Vitamin C Anti-Dark Spot Serum Reduces Hyperpigmentation, Melasma & Dark Spots

Nykaa E retail limited

Uriage Depiderm 20% Vitamin C Anti-Dark Spot Serum Reduces Hyperpigmentation, Melasma & Dark Spots

Uriage Depiderm 20% Vitamin C Anti-Dark Spot Serum Reduces Hyperpigmentation, Melasma & Dark Spots

Nykaa E retail limited

uriage-depiderm-20-vitamin-c-anti-dark-spot-serum-reduces-hyperpigmentation-melasma-dark-spots

Serum

10085071225125

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Morning
Evening
Both

How often will you use this product?

Everyday
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Every 3 days
Every 4 days
Every 5 days
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Once a week
Twice a week
On specific days
As needed
On rotation

Notes

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Compatibility Score

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Highlights

WHAT IS IT?

Anti-dark spot serum with 20% Vitamin C Complex

FEATURES

Reduces hyperpigmentation, melasma & dark spots, contains 20% Vitamin C Complex and Niacinamide

BEST FOR

sensitive

CHECKS

Alcohol-free, Silicone-free, Paraben-Free

Who Is It For?

What Does It Help With?

Hyperpigmentation Melasma Dark Spots

Budget

Premium ($76-$150)

How To Use

Which routine should it be used in?

Morning
Evening
 
Cleanse
Tone
Eyecare
Serum
Moisturize
Suncare
 

Instructions:

Apply morning & evening to the face, neck & neckline before your care. Avoid contact with eyes.

Key Information

Vegan
Cruelty-free
Sensitive-safe
Non-comedogenic
Hypoallergenic
Microbiome-safe
Preservative-free
Eco-friendly
Pregnancy-safe
Oil-free

What Nykaa E retail limited Says

Product Description:

Explore the entire range of Serums & Essence available on Nykaa. Shop more Uriage products here. You can browse through the complete world of Uriage Serums & Essence.

About the Brand:

URIAGE harnesses the healing properties of French thermal spring water that has been used therapeutically for over 300 years. Their approach involves combining this mineral-rich water with modern dermatological science to create products that soothe, heal, and protect sensitive skin. This thermal water therapy has made them trusted by dermatologists for treating various skin sensitivities and conditions.

Ingredients Overview

Ingredients List

aqua-(water-eau), glycerin, caprylyl/capryl-glucoside, polysorbate-20, parfum-(fragrance), hydroxyacetophenone, ethyl-lauroyl-arginate-hcl, citric-acid, leontopodium-alpinum-flower/leaf-extract

Key Ingredients

20% Vitamin C Complex, Niacinamide

Ingredients Details

Glycerin

Common Name(s): Glycerol,glycerine,1,2,3-propanetriol

CAS Number: 56-81-5

DESCRIPTION

What It Does: Glycerin pulls water from the environment and deeper skin layers into the outer skin layer (epidermis), boosting moisture levels and keeping skin soft, smooth, and plump.

Why It's Used: It is used in virtually every moisturizer, serum, and cleanser because it is highly effective at hydrating skin, is well-tolerated by all skin types, and enhances the texture and spreadability of formulations.

How It Works: As a humectant, glycerin forms hydrogen bonds with water molecules, trapping them in the skin. it also reinforces the skin barrier by integrating into lipid structures between skin cells.

Typically Found In: Moisturizers,serums,cleansers,toners,sheet masks,sunscreens,body lotions,shampoos,conditioners

TECHNICAL DETAILS

Primary Category: Humectant

Secondary Functions: Skin barrier support,emollient,solvent

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%โ€“30% (typical: 3โ€“10%)

SOURCING & ETHICS

Vegan Status: Yes โ€“ plant-derived (coconut, soy, palm) or synthetic

Halal Status: Yes โ€“ when plant-derived or synthetic; verify source with supplier

Source Notes: Derived from plant oils via hydrolysis or saponification; synthetic versions also available. palm-derived glycerin carries sustainability concerns.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low; non-irritating at all standard concentrations

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Extremely rare allergic reactions; generally safe for all skin types including sensitive and baby skin

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Widely recognized as safe. ewg hazard score: 1. no significant concerns for irritation, sensitization, or toxicity at typical concentrations (up to 50%).

Works Well With: Hyaluronic acid,ceramides,niacinamide,panthenol,urea,peptides,retinol,ahas/bhas

Avoid Combining With: No known incompatibilities at standard concentrations

SCIENTIFIC NOTE

Glycerin is an endogenous skin component found naturally in the stratum corneum. aquaporin-3 channels in keratinocytes facilitate glycerin transport, making it integral to natural skin hydration pathways.

Last Verified: Cosing database,cir safety assessment,ewg skin deep,inci decoder

Primary Sources: 2026-03-12

Hydroxyacetophenone

Common Name(s): Para-hydroxyacetophenone,piceol,4-acetylphenol

CAS Number: 99-93-4

DESCRIPTION

What It Does: Provides antioxidant and preservative-boosting activity in a naturally-occurring clean-label phenolic.

Why It's Used: Clean-label preservation support โ€” hydroxyacetophenone provides antioxidant and antimicrobial-boosting properties from a naturally-occurring compound accepted in natural cosmetic certifications.

How It Works: Para-hydroxyl group provides antioxidant radical scavenging. disrupts bacterial cell membrane penetration for preservative system boosting. anti-inflammatory via nf-kb inhibition. occurs naturally in plants including pear and raspberry as a secondary metabolite.

Typically Found In: Natural preservation systems,antioxidant serums,clean beauty

TECHNICAL DETAILS

Primary Category: Functional ingredient โ€“ antioxidant preservative booster

Secondary Functions: Free radical scavenging,anti-aging

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%โ€“1%

SOURCING & ETHICS

Vegan Status: Yes โ€“ natural from plants or synthetic

Halal Status: Yes

Source Notes: Plant-derived extract or synthetic.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Non-irritating; well-tolerated.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Hydroxyacetophenone's natural occurrence in fruits (pear, raspberry, passion fruit) at detectable concentrations provides clean-label justification for use in natural cosmetics. its cosmos certification acceptance reflects the growing demand for functional preservation ingredients that meet natural certification criteria โ€” an ingredient with genuine plant-origin credentials that provides meaningful antimicrobial and antioxidant functions simultaneously.

Last Verified: Cosing database,cosmos-standard approved ingredients,cir safety assessment

Primary Sources: 2026-03-12