Vitamin C Ester Daily Brightening & Exfoliating Peel

Perricone MD

Vitamin C Ester Daily Brightening & Exfoliating Peel

Vitamin C Ester Daily Brightening & Exfoliating Peel

Perricone MD

vitamin-c-ester-daily-brightening-exfoliating-peel

Exfoliation

9643625578789

Morning or Evening?

Morning
Evening
Both

How often will you use this product?

Everyday
Every other day
Every 3 days
Every 4 days
Every 5 days
Every 6 days
Once a week
Twice a week
On specific days
As needed
On rotation

Notes

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Compatibility Score

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Ingredients
Biological
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Highlights

WHAT IS IT?

Liquid exfoliating peel with multiple ingredients

FEATURES

No-rinse, resurfacing, brightening, smoothing, fast-absorbing

BEST FOR

Not explicitly mentioned, but suitable for daily use

CHECKS

Not explicitly mentioned

Who Is It For?

Adults (inferred Specific Age Range Not Provided) Both Men And Women (inferred)

What Does It Help With?

Eliminates Dead Skin Cells Smooths Uneven Texture Improves Radiance And Glow Reduces Discoloration And Dark Spots

Budget

Mid-range

How To Use

Which routine should it be used in?

Morning
Evening
 
Cleanse
Tone
Eyecare
Serum
Moisturize
Suncare
 

Instructions:

Not provided in the given information

Key Information

Vegan
Cruelty-free
Sensitive-safe
Non-comedogenic
Hypoallergenic
Microbiome-safe
Preservative-free
Eco-friendly
Pregnancy-safe
Oil-free

What Perricone MD Says

Product Description:

An advanced, no-rinse resurfacing peel that helps eliminate dead skin cells and smooth uneven texture, while instantly improving skin's radiance and glow. Gentle enough to use daily, this lightweight, fast-absorbing liquid peel helps visibly brighten, tighten and reduce the appearance of discoloration and dark spots over time to promote a visibly healthy, luminous-looking complexion.

About the Brand:

Founded by Dr. Nicholas Perricone, Perricone MD is a pioneer in the science of aging. This brand takes a holistic approach to skincare, combining cutting-edge ingredients with a focus on nutrition and lifestyle. Experience transformative results with products that address not just the signs of aging, but its underlying causes.

Ingredients Overview

Ingredients List

Water/Aqua/Eau, Propanediol, Glycolic Acid, 3-O-Ethyl Ascorbic Acid, Gluconolactone, PEG-8 Dimethicone, Vaccinium Myrtillus Fruit Extract, PPG-26-Buteth-26, Sodium Hydroxide, PEG-40 Hydrogenated Castor Oil, 1,2-Hexanediol, Saccharum Officinarum (Sugarcane) Extract/Extrait De Canne ร€ Sucre, Ferulic Acid, Citrus Aurantium Dulcis (Orange) Fruit Extract, Citrus Limon (Lemon) Fruit Extract, Sodium Benzoate, Sodium Phytate, Tetrahexyldecyl Ascorbate, Acer Saccharum (Sugar Maple) Extract.

Key Ingredients

Vitamin C Ester, AHA / PHA Super Blend, Ferulic Acid

Ingredients Details

3-o Ethyl Ascorbic Acid

Common Name(s): Ethyl ascorbic acid,3-o-ea,vitamin c ether

DESCRIPTION

What It Does: Provides stable vitamin c activity combining formulation stability with good skin delivery.

Why It's Used: Best balance of stability and bioavailability among vitamin c derivatives โ€” 3-o-ea provides stability superior to ascorbic acid with better bioavailability than large ester forms like ascorbyl tetraisopalmitate.

How It Works: C3 ether position protection prevents oxidation at the most vulnerable c2-c3 enediol. more lipophilic than ascorbic acid for improved skin penetration. ether bond resistant to hydrolysis in formulation but cleaved by skin esterases for active ascorbic acid release in viable epidermis.

Typically Found In: Stable brightening serums,anti-aging vitamin c products

TECHNICAL DETAILS

Primary Category: Active ingredient โ€“ ethyl ascorbic acid

Secondary Functions: Tyrosinase inhibitor,collagen cofactor

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%โ€“3%

SOURCING & ETHICS

Vegan Status: Yes โ€“ synthetic

Halal Status: Yes

Source Notes: Synthetically produced vitamin c derivative.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Non-irritating; suitable for all skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Tocopherol,ferulic acid,niacinamide,spf

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

3-o-ethyl ascorbic acid's ether bond at c3 provides fundamentally different stability vs ester-bonded vitamin c derivatives (ascorbyl palmitate, ascorbyl tetraisopalmitate). ether bonds are far more resistant to chemical hydrolysis than ester bonds โ€” 3-o-ea is more hydrolysis-stable than c6 ester derivatives while still providing bioactive release via ether cleavage in skin.

Last Verified: Cosing database,cir safety assessment

Primary Sources: 2026-03-12

Gluconolactone

Common Name(s): D-gluconolactone,delta-gluconolactone

CAS Number: 90-80-2

DESCRIPTION

What It Does: Provides the gentlest chemical exfoliation with simultaneous antioxidant, moisture retention, and barrier support.

Why It's Used: Preferred exfoliant for rosacea, eczema, sensitive skin, and post-procedure recovery where standard ahas cause unacceptable irritation.

How It Works: Hydrolyzes slowly on skin surface to gluconic acid providing gentle exfoliation. multiple hydroxyl groups enable water binding (humectant) and metal chelation (antioxidant).

Typically Found In: Sensitive skin exfoliants,rosacea treatments,eczema care,post-procedure recovery

TECHNICAL DETAILS

Primary Category: Active ingredient โ€“ polyhydroxy acid (pha)

Secondary Functions: Gentle exfoliation,antioxidant,humectant

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 5%โ€“15%

SOURCING & ETHICS

Vegan Status: Yes โ€“ fermentation or synthetic

Halal Status: Yes

Source Notes: Fermentation-derived from glucose or synthetic. among the safest chemical exfoliants available.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: No photosensitization; no stinging; suitable for very sensitive skin.

Safe for Sensitive Skin: Yes โ€“ ideal for sensitive, reactive, rosacea, and eczema-prone skin; no photosensitization

SAFETY & COMPATIBILITY

Safety Profile: Exceptional safety profile. no photosensitization. ewg score: 1.

Works Well With: Ceramides,niacinamide,hyaluronic acid,soothing actives

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Phas have molecular weights 2โ€“3ร— larger than ahas, limiting penetration to superficial layers. combined humectant and antioxidant properties make them uniquely well-tolerated while providing meaningful exfoliation.

Last Verified: Cosing database,green & yu (2003) pha review,cir safety assessment

Primary Sources: 2026-03-12

Glycolic Acid

Common Name(s): Hydroxyacetic acid,2-hydroxyacetic acid

CAS Number: 79-14-1

DESCRIPTION

What It Does: Provides maximum aha efficacy from the smallest most penetrating alpha-hydroxy acid.

Why It's Used: The most potent aha โ€” glycolic acid's smallest molecular size provides the deepest penetration and highest efficacy of any alpha-hydroxy acid for exfoliation and anti-aging.

How It Works: Smallest aha (mw 76) provides deepest stratum corneum penetration. disrupts corneodesmosomes reducing cohesion. stimulates fibroblast collagen i and iii synthesis. efficacy is ph-dependent โ€” free acid fraction determines activity.

Typically Found In: Chemical peels,body lotions,anti-aging serums,exfoliating toners

TECHNICAL DETAILS

Primary Category: Active ingredient โ€“ primary aha

Secondary Functions: Brightening,collagen stimulation

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%โ€“10% cosmetic; higher professional

SOURCING & ETHICS

Vegan Status: Yes โ€“ synthetic or fermentation-derived

Halal Status: Yes

Source Notes: Fermentation-derived or synthetic. ph must be โ‰ค4.0 for aha activity.

SKIN COMPATIBILITY

Irritancy Rating: 2/5 โ€“ low to moderate

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Photosensitizing โ€“ mandatory spf use. start at low frequency.

Safe for Sensitive Skin: Use with caution โ€“ spf required

SAFETY & COMPATIBILITY

Safety Profile: Eu cosmetics: max 10% leave-on, ph โ‰ฅ3.5, mandatory sun protection advisory. professional peel concentrations regulated separately.

Works Well With: Niacinamide,ceramides,hyaluronic acid,spf

Avoid Combining With: Retinol in same step; multiple exfoliants simultaneously

SCIENTIFIC NOTE

Glycolic acid's ph-dependent efficacy is critical: at ph 3.0 ~100% is in the free acid (membrane-permeable) form; at ph 3.5 ~70%; at ph 4.0 ~50%. the eu ph โ‰ฅ3.5 requirement reduces free acid proportion, lowering efficacy but also reducing irritation โ€” why professional peel concentrations at lower ph are far more active than equivalent cosmetic concentrations.

Last Verified: Cosing database,eu aha guidelines,cir safety assessment

Primary Sources: 2026-03-12

Peg-40 Hydrogenated Castor Oil

Common Name(s): Peg-based nonionic emulsifier,ethoxylate surfactant,o/w solubiliser

CAS Number: N/a

DESCRIPTION

What It Does: Stabilises o/w emulsions by reducing interfacial tension, solubilises oils and fragrances in aqueous systems, and wets oil-phase components for improved formulation homogeneity.

Why It's Used: Peg emulsifiers are selected for their precise hlb, broad ph stability (unlike soap emulsifiers that lose function at acidic ph), and compatibility with both anionic and cationic co-ingredients in the formulation system.

How It Works: Peg chain length determines hlb: longer peg = higher hlb = more hydrophilic = better o/w emulsification. at the o/w interface, the peg chain extends into the water phase forming a hydrated steric barrier that prevents droplet coalescence. nonionic character provides ph-independent function across the full cosmetic ph range.

Typically Found In: Emulsions,fragrance solubilisation

TECHNICAL DETAILS

Primary Category: Active ingredient โ€“ cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%โ€“10%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1โ€“2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Mixed peg emulsifier systems (e.g., peg-100 stearate + glyceryl stearate) form more cohesive interfacial films than single emulsifiers โ€” the geometric complementarity of the co-emulsifier pair providing better mechanical emulsion stability than either component alone.

Last Verified: Cosing database,peg-40 hydrogenated castor oil peg emulsifier review

Primary Sources: 2026-03-12