Vitamin K Serum 0.5 fl oz

DESCRIPTION

What It Does: Lightweight, stable emollient that solubilizes oil-soluble actives for excellent delivery without greasy feel.

Why It's Used: Universal lightweight emollient base and solubilizer for oil-soluble actives in serums and low-viscosity formulations where mineral oil or petrolatum would be too heavy.

How It Works: Medium-chain length provides ideal balance of spreading coefficient, penetration rate, and barrier-sealing properties. excellent solubilizer for vitamin e, retinoids, and other lipophilic actives.

Typically Found In: Serums,facial oils,sunscreens,anti-aging products,hair products

TECHNICAL DETAILS

Primary Category: Active ingredient – medium-chain triglyceride emollient

Secondary Functions: Active solubilizer,spreading agent

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%–50%

SOURCING & ETHICS

Vegan Status: Yes – from coconut/palm kernel oil

Halal Status: Yes

Source Notes: Fractionated by hydrolysis and re-esterification of coconut oil. only c8 and c10 fatty acids retained.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 1/5 – very low; medium-chain length generally non-comedogenic

Sensitivity Concerns: Non-irritating.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Humectants,ceramides,actives as carrier

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Mct oil's medium-chain length (c8/c10) provides superior oxidative stability vs longer polyunsaturated chains and better skin aesthetics (lighter, less greasy) vs longer chain emollients (c16/c18). excellent solubilizer for retinoic acid, tocopheryl esters, and other lipophilic actives.

Last Verified: Cosing database,cir safety assessment,ewg skin deep

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides antioxidant protection from reactive oxygen species, reduces inflammatory cytokine production in skin, and conditions skin surface through the plant's secondary metabolite complex.

Why It's Used: Chosen for its natural origin narrative, traditional use heritage, and multi-functional phytochemical profile that supports several concurrent skin care claims from one ingredient.

How It Works: Polyphenols, terpenoids, and alkaloids in the extract scavenge ros via hydrogen atom transfer, inhibit nf-kb or cox-2 inflammatory pathways, and interact with skin surface proteins for conditioning.

Typically Found In: Botanical skin care,natural products

TECHNICAL DETAILS

Primary Category: Active ingredient – antioxidant

Secondary Functions: Free radical scavenging,anti-aging

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–10%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Plant-derived extract or synthetic.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; well-tolerated.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Plant secondary metabolites evolved as uv photoprotectants and antimicrobial agents — mechanisms that directly translate to cosmetic antioxidant and anti-inflammatory activity in human skin.

Last Verified: Cosing database,cocos nucifera (coconut) fruit extr botanical review

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Glycerin pulls water from the environment and deeper skin layers into the outer skin layer (epidermis), boosting moisture levels and keeping skin soft, smooth, and plump.

Why It's Used: It is used in virtually every moisturizer, serum, and cleanser because it is highly effective at hydrating skin, is well-tolerated by all skin types, and enhances the texture and spreadability of formulations.

How It Works: As a humectant, glycerin forms hydrogen bonds with water molecules, trapping them in the skin. it also reinforces the skin barrier by integrating into lipid structures between skin cells.

Typically Found In: Moisturizers,serums,cleansers,toners,sheet masks,sunscreens,body lotions,shampoos,conditioners

TECHNICAL DETAILS

Primary Category: Humectant

Secondary Functions: Skin barrier support,emollient,solvent

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%–30% (typical: 3–10%)

SOURCING & ETHICS

Vegan Status: Yes – plant-derived (coconut, soy, palm) or synthetic

Halal Status: Yes – when plant-derived or synthetic; verify source with supplier

Source Notes: Derived from plant oils via hydrolysis or saponification; synthetic versions also available. palm-derived glycerin carries sustainability concerns.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low; non-irritating at all standard concentrations

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Extremely rare allergic reactions; generally safe for all skin types including sensitive and baby skin

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Widely recognized as safe. ewg hazard score: 1. no significant concerns for irritation, sensitization, or toxicity at typical concentrations (up to 50%).

Works Well With: Hyaluronic acid,ceramides,niacinamide,panthenol,urea,peptides,retinol,ahas/bhas

Avoid Combining With: No known incompatibilities at standard concentrations

SCIENTIFIC NOTE

Glycerin is an endogenous skin component found naturally in the stratum corneum. aquaporin-3 channels in keratinocytes facilitate glycerin transport, making it integral to natural skin hydration pathways.

Last Verified: Cosing database,cir safety assessment,ewg skin deep,inci decoder

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides o/w emulsification with emolliency and skin feel improvement from a natural glycerol ester.

Why It's Used: Standard cosmetic monoglyceride emulsifier – widely used for o/w cream formation with clean, natural-origin credentials and good sensory profile.

How It Works: Monoglyceride structure (one fatty acid + glycerol) provides amphiphilic hlb ~3-4 for o/w emulsification when combined with higher hlb co-emulsifiers. forms alpha-gel lamellar structure with water for emulsion stabilization. direct skin conditioning via fatty acid film.

Typically Found In: Creams,lotions,moisturizers – standard in o/w emulsions

TECHNICAL DETAILS

Primary Category: Functional ingredient – monoglyceride emulsifier

Secondary Functions: Barrier sealing,softening

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%–10%

SOURCING & ETHICS

Vegan Status: Yes – from vegetable glycerol and stearic acid

Halal Status: Yes

Source Notes: Plant-derived, synthetic or animal-derived. verify source.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 1/5 – low; formulation-dependent

Sensitivity Concerns: Non-irritating.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Humectants,ceramides,actives as carrier

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Glyceryl stearate's alpha-gel lamellar phase formation (distinguishable by x-ray crystallography from beta crystalline phase) provides superior emulsion stability compared to its beta crystalline form. the alpha-gel phase creates a viscoelastic network that resists droplet coalescence – the fundamental mechanism behind gms's long use as a reliable primary emulsifier.

Last Verified: Cosing database,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Delivers characteristic cosmetic function — skin conditioning, antioxidant protection, active biological benefit, or formulation function — at recommended use concentration.

Why It's Used: Selected for functional contribution and formulation compatibility supported by cosmetic science and regulatory safety data.

How It Works: Works through the mechanism of its molecular class — physicochemical or biological interaction with skin proteins, lipids, or receptors as documented in peer-reviewed cosmetic literature.

Typically Found In: Skin care formulations

TECHNICAL DETAILS

Primary Category: Active ingredient – cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–10%

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Jojoba esters has an established safety and efficacy profile within the cosmetic regulatory framework at standard use concentrations.

Last Verified: Cosing database,jojoba esters technical literature

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides high-hlb o/w emulsification as a co-emulsifier partner in standard cream formulations.

Why It's Used: Standard high-hlb co-emulsifier for gms/fatty alcohol/peg-100 stearate classic cream formulation systems.

How It Works: High peg chain length provides hlb ~18 for strong water-phase affinity. combined with low-hlb gms (hlb ~3) at appropriate ratio achieves target hlb for stable o/w emulsification. high hydrophilicity also provides solubilization of oil-soluble ingredients.

Typically Found In: Classic creams and lotions

TECHNICAL DETAILS

Primary Category: Functional ingredient – peg ester emulsifier

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.5%–5%

SOURCING & ETHICS

Vegan Status: Conditional – peg from petroleum; stearate from vegetable

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Eu cosmetics regulation: peg compounds may contain 1,4-dioxane impurity from peg manufacture. quality-grade peg-100 stearate should have <10ppm 1,4-dioxane.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Peg-100 stearate's hlb value of ~18 paired with gms's hlb of ~3 provides the classic 'required hlb matching' for emulsification of common cosmetic oils. when combined at approximately a 1:3 gms:peg-100 ratio, the blended hlb (~7) matches the required hlb of most mineral and vegetable oils, providing the theoretical basis for one of the most widely used cream formulation systems.

Last Verified: Cosing database,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Reduces bruising and dark circles in post-procedure and eye care applications at pharmaceutical purity.

Why It's Used: Pharmaceutical-grade vitamin k1 in higher-potency preparations for clinical skincare and post-procedure recovery.

How It Works: Identical mechanism to phylloquinone – activates vitamin k-dependent proteins through gamma-carboxylation of glutamic acid.

Typically Found In: Post-procedure skincare,eye creams,bruise healing,laser aftercare

TECHNICAL DETAILS

Primary Category: Active ingredient – vitamin k1 (pharmaceutical grade)

Secondary Functions: Dark circle reduction,bruise healing

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–1%

SOURCING & ETHICS

Vegan Status: Yes – synthetic or plant-derived

Halal Status: Yes

Source Notes: Pharmaceutical designation indicates usp/ep purity grade vs cosmetic-grade phylloquinone (same compound).

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating at cosmetic concentrations.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1. caution for patients on warfarin.

Works Well With: Retinol,caffeine,peptides,ceramides

Avoid Combining With: Warfarin anticoagulant therapy (consult physician)

SCIENTIFIC NOTE

The pharmaceutical designation 'phytonadione' indicates higher purity grade ensuring consistent potency for clinical applications. both phytonadione and phylloquinone are chemically identical – vitamin k1.

Last Verified: Cosing database,usp monograph,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides low-hlb w/o emulsification for stable water-in-oil cream systems.

Why It's Used: Low-hlb emulsifier for w/o cream formulations requiring water-in-oil texture with good skin occlusion.

How It Works: Hlb ~4.7 provides w/o emulsification tendency. stearate (c18) chain provides solid wax-like texture. when combined with polysorbate 60 or 80 (high hlb) at appropriate ratios achieves target hlb for oil type being emulsified.

Typically Found In: W/o creams,sunscreens,thick barrier creams

TECHNICAL DETAILS

Primary Category: Functional ingredient – low-hlb w/o emulsifier

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.5%–5%

SOURCING & ETHICS

Vegan Status: Yes – from sorbitol and stearic acid (plant)

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Sorbitan stearate's transition from w/o to o/w emulsifier tendency when combined with polysorbate 60 at the classic 1:3 span:tween ratio was the original experimental basis for griffin's hlb (hydrophile-lipophile balance) theory. the span-tween system's systematic hlb tunability by ratio adjustment made it the experimental model for understanding blended emulsifier systems.

Last Verified: Cosing database,griffin hlb original paper,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Replenishes age-declining coq10 for mitochondrial energy support and membrane antioxidant protection.

Why It's Used: The mitochondrial anti-aging ingredient — coq10 skin levels decrease ~50% from age 20 to 80 and topical supplementation directly addresses this documented decline.

How It Works: Ubiquinone/ubiquinol redox cycle carries electrons in mitochondrial complexes i–iii for atp production. reduced ubiquinol quenches lipid peroxyl radicals in inner mitochondrial membrane. coq10 depletion in aging skin reduces atp production and membrane antioxidant defence simultaneously.

Typically Found In: Anti-aging serums,mitochondrial skincare,antioxidant products

TECHNICAL DETAILS

Primary Category: Active ingredient – antioxidant

Secondary Functions: Free radical scavenging,anti-aging

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.01%–1%

SOURCING & ETHICS

Vegan Status: Yes – from fermentation or synthetic

Halal Status: Yes

Source Notes: Plant-derived extract or synthetic.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; well-tolerated.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Coq10's mitochondrial role places it at the nexus of aging biology — a 50% decline from age 20 to 80 is mechanistically linked to reduced atp production, increased mitochondrial superoxide leak, and mtdna damage constituting the 'mitochondrial theory of aging' at the cellular level.

Last Verified: Cosing database,shindo et al. coq10 skin aging study

Primary Sources: 2026-03-12